Evidence map›Paper›PMID 29898997›Full record

ArticleJournal of clinical microbiology2018

Revisiting the Lyme Disease Serodiagnostic Algorithm: the Momentum Gathers.

Adriana R Marques

Registry-linked trialOpen access · bronzeAbstract readComment
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04318925 (Evaluation and Follow-up of Patients With Tick-borne Diseases), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04318925 withdrawnnot on this mapstarted 2023, after this paper: background citation

Evaluation and Follow-up of Patients With Tick-borne Diseases

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2023 to 2023Enrolled0ConditionsLyme Disease, Tick-Borne Disease
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Review
  13. Laboratory Diagnosis of Lyme Borreliosis.Clinical microbiology reviews · 2021
    Review
  14. Article
  15. Lyme Disease Pathogenesis.Current issues in molecular biology · 2021
    Review
  16. Article
  17. Review
  18. Modified two-tiered testing algorithm for Lyme disease serology: the Canadian context.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Adriana R MarquesLyme Disease Studies Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA amarques@niaid.nih.gov.ORCID 0000-0002-5403-4551
National Institutes of Health · US

Funding

Assessment Of Patients With Borrelia InfectionZIAAI000695 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARQUES, ADRIANA R · 2009 to 2025
$8.8M
6 · The paper itself

Abstract

Lyme disease is a tick-borne illness caused by

Indexed as

Lyme DiseaseAlgorithmsAntibodies, BacterialBorrelia burgdorferiHumansImmunoglobulin GSensitivity and SpecificitySerologic TestsAntibodies, BacterialImmunoglobulin G

Identifiers

PMID29898997
PMCPMC6062820
OpenAlexW2808631016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.