Evidence map›Paper›PMID 29898983›Full record

ArticlemSphere2018

Potential Mechanism of Detoxification of Cyanide Compounds by Gut Microbiomes of Bamboo-Eating Pandas.

Lifeng Zhu, Zhisong Yang, Ran Yao, Liangliang Xu, Hua Chen, Xiaodong Gu, Tonggui Wu, Xuyu Yang

Abstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Dynamic Impacts of Stock Enhancement on Kaluga Sturgeon (International journal of molecular sciences · 2025
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  20. Microbiology spectrum · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lifeng Zhu *College of Life Sciences, Nanjing Normal University, Nanjing, China lzhu@unomaha.edu.ORCID 0000-0002-0589-4256
Zhisong Yang *Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), China West Normal University, Nanchong, China.
Ran YaoCollege of Life Sciences, Nanjing Normal University, Nanjing, China.
Liangliang XuCollege of Life Sciences, Nanjing Normal University, Nanjing, China.
Hua ChenShanghai Biozeron Bioinformatics Center, Shanghai, China.
Xiaodong GuSichuan Station for Wildlife Survey and Management, Chengdu, China.
Tonggui WuEast China Coastal Forest Ecosystem Long-Term Research Station, Research Institute of Subtropical Forestry, Chinese Academy of Forestry, Fuyang, Zhejiang, China.
Xuyu YangSichuan Station for Wildlife Survey and Management, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbes can enhance the ability of hosts to consume secondary plant compounds and, therefore, expand the dietary niche breadth of mammalian herbivores. The giant and red pandas are bamboo-eating specialists within the mammalian order Carnivora. Bamboo contains abundant plant secondary metabolites (e.g., cyanide-containing compounds). However, Carnivora species, including the giant panda, have deficient levels of rhodanese (one of the essential cyanide detoxification enzymes) in their tissues compared with the same tissues of herbivores. Here, we make a comparative analysis of 94 gut metagenomes, including 25 from bamboo-eating pandas (19 from giant pandas and 6 from red pandas), 30 from Père David's deer, and 39 from published data for other mammals. The bamboo-eating pandas' gut microbiomes had some common features, such as high proportions of

Indexed as

Gastrointestinal MicrobiomeAiluridaeAnimalsBacteriaBiotransformationCyanidesMetagenomicsUrsidaeCyanidesbamboocomparative genomicscyanide compound detoxificationgut microbial metagenomespandas

Identifiers

PMID29898983
PMCPMC6001608

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.