Evidence map›Paper›PMID 29898964›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.

Kyoko Hayakawa, Anthony M Formica, Yuka Nakao, Daiju Ichikawa, Susan A Shinton, Joni Brill-Dashoff, Mitchell R Smith, Herbert C Morse, Richard R Hardy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Neonatal CD19Frontiers in immunology · 2026
    Article
  2. Do human B-1 lymphocytes truly exist?Frontiers in immunology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kyoko HayakawaFox Chase Cancer Center, Philadelphia, PA 19111; Kyoko.Hayakawa@fccc.edu.ORCID 0000-0003-3157-5897
Anthony M FormicaFox Chase Cancer Center, Philadelphia, PA 19111.
Yuka NakaoFox Chase Cancer Center, Philadelphia, PA 19111.
Daiju IchikawaFox Chase Cancer Center, Philadelphia, PA 19111.
Susan A ShintonFox Chase Cancer Center, Philadelphia, PA 19111.ORCID 0000-0003-2649-1904
Joni Brill-DashoffFox Chase Cancer Center, Philadelphia, PA 19111.ORCID 0000-0002-8596-5877
Mitchell R SmithFox Chase Cancer Center, Philadelphia, PA 19111.ORCID 0000-0003-1428-8765
Herbert C MorseLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
Richard R HardyFox Chase Cancer Center, Philadelphia, PA 19111.
Fox Chase Cancer Center · USNational Institutes of Health · US

Funding

LY-1 B CELLS--LINEAGE DETERMINATION/ANTIBODY REPERTOIRER01AI026782 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI HARDY, RICHARD R · 1990 to 2011
$5.5M
Mechanisms regulating the B lymphopoiesis fetal/adult switchR01AI113320 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI HAYAKAWA, KYOKO · 2015 to 2019
$2.0M
Origin of CD5+ B cell Lymphoma/Leukemia in MiceR01CA129330 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI HAYAKAWA, KYOKO · 2009 to 2013
$1.8M
Generation and characterization of human B1 B cells induced by Lin28b reprogramming of adult hematopoietic progenitorsR21AI117429 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI HAYAKAWA, KYOKO · 2015 to 2016
$491k
NCI NIH HHS R01 CA129330NIAID NIH HHS R01 AI026782NIAID NIH HHS R01 AI113320NIAID NIH HHS R21 AI117429
6 · The paper itself

Abstract

In mice, fetal/neonatal B-1 cell development generates murine CD5

Indexed as

AgingAnimalsAutoantigensB-LymphocytesCarcinogenesisCell DifferentiationCyclin D1Gene Knock-In TechniquesLymphoma, Mantle-CellMiceMice, Inbred C57BLMice, TransgenicPhosphatidylcholinesReceptors, Antigen, B-CellSTAT3 Transcription FactorAutoantigensCyclin D1PhosphatidylcholinesReceptors, Antigen, B-CellSTAT3 Transcription Factor

Identifiers

PMID29898964
PMCPMC6036230
OpenAlexW2808370942

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.