Evidence map›Paper›PMID 29898916›Full record

ArticleJournal of cell science2018

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.

Susana Peralta, Steffi Goffart, Sion L Williams, Francisca Diaz, Sofia Garcia, Nadee Nissanka, Estela Area-Gomez, Jaakko Pohjoismäki, Carlos T Moraes

Abstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cholesterol in Mitochondrial Diseases-Friend or Foe?International journal of molecular sciences · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Mitochondrial Maintenance in Skeletal Muscle.Cold Spring Harbor perspectives in biology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. FAM210A: An emerging regulator of mitochondrial homeostasis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Susana PeraltaDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Steffi GoffartDepartment of Environmental and Biological Sciences, University of Eastern Finland, Joensuu 80101, Finland.
Sion L WilliamsDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Francisca DiazDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Sofia GarciaDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-3809-1510
Nadee NissankaNeuroscience Graduate Program, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Estela Area-GomezDepartment of Neurology, Columbia University Medical Center, New York, NY 10032, USA.
Jaakko PohjoismäkiDepartment of Environmental and Biological Sciences, University of Eastern Finland, Joensuu 80101, Finland.
Carlos T MoraesDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA cmoraes@med.miami.edu.ORCID 0000-0002-8077-7092

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Marco Ruggeri · 2004 to 2026
$12.2M
SETTING THE STAGE FOR REPLACEMENT OF MITOCHONDRIAL GENESR01EY010804 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORAES, CARLOS TORRES · 1995 to 2025
$9.4M
Cellular and Molecular Consequences of Respiratory Chain Defects in NeuronsR01NS079965 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORAES, CARLOS TORRES · 2012 to 2023
$3.9M
Mitochondrial Dysfunction in Neurodegeneration and Compensatory ApproachesR01AG036871 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORAES, CARLOS TORRES · 2010 to 2020
$3.3M
Role of C99 in the regulation of lipid metabolism- Relevance to Alzheimer's diseaseR01AG056387 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AREA GOMEZ, ESTELA · 2017 to 2021
$2.1M
Endoplasmic Reticulum Mitochondrial membranes in Alzheimer's diseaseK01AG045335 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AREA GOMEZ, ESTELA · 2014 to 2018
$567k
NEI NIH HHS P30 EY014801NEI NIH HHS R01 EY010804NIA NIH HHS K01 AG045335NIA NIH HHS R01 AG036871NIA NIH HHS R01 AG056387NINDS NIH HHS R01 NS079965
6 · The paper itself

Abstract

Mutations in the mitochondrial inner membrane ATPase

Indexed as

AnimalsATPases Associated with Diverse Cellular ActivitiesCholesterolDNA, MitochondrialDNA ReplicationFemaleHumansMaleMiceMice, KnockoutMitochondriaMitochondrial ProteinsMuscle DevelopmentMusclesMuscular DiseasesAtad3a protein, mouseATPases Associated with Diverse Cellular ActivitiesCholesterolDNA, MitochondrialMitochondrial ProteinsATAD3CholesterolCristaeMICOS complexMitochondriaMuscle

Identifiers

PMID29898916
PMCPMC6051345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.