Evidence map›Paper›PMID 29898891›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2018

Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer.

Molly Scannell Bryan, Maria Argos, Irene L Andrulis, John L Hopper, Jenny Chang-Claude, Kathleen E Malone, Esther M John, Marilie D Gammon, Mary B Daly, Mary Beth Terry and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. LowerBiology · 2024
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Molly Scannell BryanDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois. scannemo@uic.edu.
Maria ArgosUniversity of Illinois at Chicago, Chicago, Illinois.
Irene L AndrulisLunefeld-Tanenbaum Research Institute, Sinai Health System and Department of Molecular Genetics, University of Toronto, Toronto, Canada.
John L HopperUniversity of Melbourne, Parkville, Victoria, Australia.
Jenny Chang-ClaudeDeutsches Krebsforschungszentrum in der Helmholtz-Gemeinshaft, Heidelberg, Germany.
Kathleen E MaloneFred Hutchinson Cancer Research Center, Seattle, Washington.
Esther M JohnCancer Prevention Institute of California, Fremont, California.
Marilie D GammonUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Mary B DalyFox Chase Cancer Center, Philadelphia, Pennsylvania.
Mary Beth TerryColumbia University, New York, New York.
Saundra S BuysUniversity of Utah Salt Lake City, Salt Lake City, Utah.
Dezheng HuoDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Olofunmilayo I OlopadeDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Jeanine M GenkingerColumbia University, New York, New York.
Alice S WhittemoreStanford University, Stanford, California.
Farzana JasmineDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Muhammad G KibriyaDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Lin S ChenDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Habibul AhsanDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois.
Fred Hutch Cancer Center · USUniversity of Melbourne · AUUniversity of North Carolina at Chapel Hill · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Core-001U01CA164920 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Irene Andrulis, Sarah Violet Colonna · 2018 to 2026
$17.0M
Breast Cancer Family Registry CohortUM1CA164920 · NCI · CANCER PREVENTION INSTIT OF CALIFORNIA · PI ANDRULIS, IRENE, BUYS, SAUNDRA S · 2012 to 2017
$12.7M
Epidemiologic StudiesU19CA148065 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI AHSAN, HABIBUL, BRUGGE, JOAN SIEFERT · 2010 to 2014
$10.6M
UIC CANCER PREVENTION &CONTROL RESEARCH TRAINING GRANTR25CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FITZGIBBON, MARIAN L. · 1992 to 2017
$8.2M
Statistical Methods for Genetic EpidemiologyR01CA094069 · NCI · STANFORD UNIVERSITY · PI WHITTEMORE, ALICE · 2002 to 2016
$7.7M
Genomewide association in early-onset breast cancerU01CA122171 · NCI · UNIVERSITY OF CHICAGO · PI AHSAN, HABIBUL · 2006 to 2010
$7.2M
Integrative multivariate association and genomic analysesR01GM108711 · NIGMS · UNIVERSITY OF CHICAGO · PI CHEN, LIN · 2014 to 2022
$3.1M
Cancer Health Equity Career Development ProgramT32CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Marian L. Fitzgibbon · 2018 to 2026
$3.0M
BREAST CANCER AND THE ENVIRONMENT ON LONG ISLANDU01CA066572 · NCI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI GAMMON, MARILIE D · 1995 to 2004
$1.7M
Genomewide Determinants Of Prognosis And Treatment Of Early-Onset Breast CancerRC1CA145506 · NCI · UNIVERSITY OF CHICAGO · PI AHSAN, HABIBUL · 2009 to 2010
$999k
Cancer Research UK C1287/A10118Cancer Research UK C1287/A10710Cancer Research UK C1287/A16563CIHRNCI NIH HHS R01 CA094069NCI NIH HHS R25 CA057699NCI NIH HHS RC1 CA145506NCI NIH HHS T32 CA057699NCI NIH HHS U01 CA066572NCI NIH HHS U01 CA122171NCI NIH HHS U01 CA164920NCI NIH HHS U19 CA148065NCI NIH HHS UM1 CA164920NIEHS NIH HHS P30 ES009089NIGMS NIH HHS R01 GM108711
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideBiomarkers, TumorBreast NeoplasmsExome SequencingFemaleFollow-Up StudiesGenome-Wide Association StudyGenotypeHumansIncidenceMiddle AgedPrognosisBiomarkers, Tumor

Identifiers

PMID29898891
PMCPMC6125194
OpenAlexW2808572698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.