Evidence map›Paper›PMID 29897885›Full record

ArticleJournal of integrative bioinformatics2018

MIRATE: MIps RATional dEsign Science Gateway.

Mirko Busato, Rosario Distefano, Ferdia Bates, Kal Karim, Alessandra Maria Bossi, José Manuel López Vilariño, Sergey Piletsky, Nicola Bombieri, Alejandro Giorgetti

Abstract read
In one paragraph

Article in Journal of integrative bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mirko BusatoDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Rosario DistefanoDepartment Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Ferdia BatesInstitute of Technological Investigations, University of Coruña (UDC), Campus Esteiro, Ferrol 15402, Spain.
Kal KarimLeicester Biotechnology Group, Department of Chemistry, University of Leicester, LE1 7RH, Leicester, UK.
Alessandra Maria BossiDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
José Manuel López VilariñoInstitute of Technological Investigations, University of Coruña (UDC), Campus Esteiro, Ferrol 15402, Spain.
Sergey PiletskyLeicester Biotechnology Group, Department of Chemistry, University of Leicester, LE1 7RH, Leicester, UK.
Nicola BombieriDepartment Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Alejandro GiorgettiDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecularly imprinted polymers (MIPs) are high affinity robust synthetic receptors, which can be optimally synthesized and manufactured more economically than their biological equivalents (i.e. antibody). In MIPs production, rational design based on molecular modeling is a commonly employed technique. This mostly aids in (i) virtual screening of functional monomers (FMs), (ii) optimization of monomer-template ratio, and (iii) selectivity analysis. We present MIRATE, an integrated science gateway for the intelligent design of MIPs. By combining and adapting multiple state-of-the-art bioinformatics tools into automated and innovative pipelines, MIRATE guides the user through the entire process of MIPs' design. The platform allows the user to fully customize each stage involved in the MIPs' design, with the main goal to support the synthesis in the wet-laboratory. Availability: MIRATE is freely accessible with no login requirement at http://mirate.di.univr.it/. All major browsers are supported.

Indexed as

HepcidinsHumansMolecular Dynamics SimulationMolecular ImprintingPolymersReceptors, ArtificialTroponin Ihepcidin 25, humanHepcidinsPolymersReceptors, ArtificialTroponin Idockingmolecularly imprinted polymersscience gateway

Identifiers

PMID29897885
PMCPMC6348745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.