Evidence map›Paper›PMID 29897862›Full record

ReviewJournal of neurophysiology2018

Stimulus-dependent engagement of neural mechanisms for reliable motion detection in the mouse retina.

Qiang Chen, Wei Wei

Abstract readReview
In one paragraph

Review in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Synaptic inputs to broad thorny ganglion cells in macaque retina.The Journal of comparative neurology · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qiang ChenDepartment of Neurobiology, The University of Chicago , Chicago, Illinois.
Wei WeiDepartment of Neurobiology, The University of Chicago , Chicago, Illinois.

Funding

Synaptic basis of motion detection in the retinaR01EY024016 · NEI · UNIVERSITY OF CHICAGO · PI WEI, WEI · 2014 to 2018
$1.9M
NEI NIH HHS R01 EY024016
6 · The paper itself

Abstract

Direction selectivity is a fundamental computation in the visual system and is first computed by the direction-selective circuit in the mammalian retina. Although landmark discoveries on the neural basis of direction selectivity have been made in the rabbit, many technological advances designed for the mouse have emerged, making this organism a favored model for investigating the direction-selective circuit at the molecular, synaptic, and network levels. Studies using diverse motion stimuli in the mouse retina demonstrate that retinal direction selectivity is implemented by multilayered mechanisms. This review begins with a set of central mechanisms that are engaged under a wide range of visual conditions and then focuses on additional layers of mechanisms that are dynamically recruited under different visual stimulus conditions. Together, recent findings allude to an emerging theme: robust motion detection in the natural environment requires flexible neural mechanisms.

Indexed as

MotionAnimalsMiceModels, NeurologicalPhotic StimulationReceptors, Metabotropic GlutamateRetinaRetinal Ganglion CellsVision, Ocularmetabotropic glutamate receptor 2Receptors, Metabotropic Glutamatedirection selectivitymotion detectionretinasynaptic circuitvisual motion

Identifiers

PMID29897862
PMCPMC6171070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.