ArticleSchizophrenia bulletin2019
Shared and Distinct Functional Architectures of Brain Networks Across Psychiatric Disorders.
Article in Schizophrenia bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Shared and distinct brain fMRI response during performance of working memory tasks in adult patients with schizophrenia and major depressive disorder.Human brain mapping · 2021Pooled it
- Changes in the structural brain connectome over the course of a nonrandomized clinical trial for acute mania.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Trial
- Shared subcortical-default mode morphological dysconnectivity in adolescent bipolar disorder, major depressive disorder and schizophrenia.Communications biology · 2026Article
- Identifying transdiagnostic neurobiomarkers for precision major psychiatric disordersJournal of translational internal medicine · 2026Article
- Cross-Disease Classification of Depression, Bipolar Disorder, and Schizophrenia Using Multiscale Spatiotemporal Network Fusion Features From fNIRS.Depression and anxiety · 2026Article
- Large-scale brain mediation network based on resting-state functional MRI.Communications biology · 2025Article
- Schizophrenia and Neurodevelopment: Insights From Connectome Perspective.Schizophrenia bulletin · 2025Review
- Increased individual variability in functional connectivity of the default mode network and its genetic correlates in major depressive disorder.Scientific reports · 2025Article
- Common and disease-specific patterns of functional connectivity and topology alterations across unipolar and bipolar disorder during depressive episodes: a transdiagnostic study.Translational psychiatry · 2025Article
- Common neuroanatomical differential factors underlying heterogeneous gray matter volume variations in five common psychiatric disorders.Communications biology · 2025Article
- Bridging animal models and humans: neuroimaging as intermediate phenotypes linking genetic or stress factors to anhedonia.BMC medicine · 2025Article
- White matter functional connectome gradient dysfunction in major depressive disorder.Psychoradiology · 2025Article
- Neuronal Synaptic Communication and Mitochondrial Energetics in Human Health and Disease.Advances in experimental medicine and biology · 2025Review
- Characterizing Psychiatric Disorders Through Graph Neural Networks: A Functional Connectivity Analysis of Depression and Schizophrenia.Depression and anxiety · 2025Article
- Functional network characteristics in adolescent psychotic mood disorder: associations with symptom severity and treatment effects.European child & adolescent psychiatry · 2024Article
- The overlap across psychotic disorders: A functional network connectivity analysis.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2024Article
- Beta-informativeness-diffusion multilayer graph embedding for brain network analysis.Frontiers in neuroscience · 2024Article
- Examining Neural Connectivity in Schizophrenia Using Task-Based EEG: A Graph Theory Approach.Sensors (Basel, Switzerland) · 2023Article
- Aberrant Large-Scale Network Interactions Across Psychiatric Disorders Revealed by Large-Sample Multi-Site Resting-State Functional Magnetic Resonance Imaging Datasets.Schizophrenia bulletin · 2023Article
- IABC: A Toolbox for Intelligent Analysis of Brain Connectivity.Neuroinformatics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain network alterations have increasingly been implicated in schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). However, little is known about the similarities and differences in functional brain networks among patients with SCZ, BD, and MDD. A total of 512 participants (121 with SCZ, 100 with BD, 108 with MDD, and 183 healthy controls, matched for age and sex) completed resting-state functional magnetic resonance imaging at a single site. Four global measures (the clustering coefficient, the characteristic shortest path length, the normalized clustering coefficient, and the normalized characteristic path length) were computed at a voxel level to quantify segregated and integrated configurations. Inter-regional functional associations were examined based on the Euclidean distance between regions. Distance strength maps were used to localize regions with altered distances based on functional connectivity. Patient groups exhibited shifts in their network architectures toward randomized configurations, with SCZ>BD>MDD in the degree of randomization. Patient groups displayed significantly decreased short-range connectivity and increased medium-/long-range connectivity. Decreases in short-range connectivity were similar across the SZ, BD, and MDD groups and were primarily distributed in the primary sensory and association cortices and the thalamus. Increases in medium-/long-range connectivity were differentially localized within the prefrontal cortices among the patient groups. We highlight shared and distinct connectivity features in functional brain networks among patients with SCZ, BD, and MDD, which expands our understanding of the common and distinct pathophysiological mechanisms and provides crucial insights into neuroimaging-based methods for the early diagnosis of and interventions for psychiatric disorders.
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