Evidence map›Paper›PMID 29897343›Full record

ArticlePhysiological measurement2018

A comparison of entropy approaches for AF discrimination.

Chengyu Liu, Julien Oster, Erik Reinertsen, Qiao Li, Lina Zhao, Shamim Nemati, Gari D Clifford

Abstract readComparative Study
In one paragraph

Article in Physiological measurement, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [Artificial intelligence in wearable electrocardiogram monitoring].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
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  6. Article
  7. Article
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  9. Article
  10. Review
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  12. Article
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  14. Article
  15. A Review of Atrial Fibrillation Detection Methods as a Service.International journal of environmental research and public health · 2020
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengyu LiuThe State Key Laboratory of Bioelectronics, Jiangsu Key Lab of Remote Measurement and Control, School of Instrument Science and Engineering, Southeast University, Nanjing, People's Republic of China.ORCID 0000-0003-1965-3020
Julien OsterInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
Erik ReinertsenDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States of America.
Qiao LiDepartment of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.
Lina ZhaoThe State Key Laboratory of Bioelectronics, Jiangsu Key Lab of Remote Measurement and Control, School of Instrument Science and Engineering, Southeast University, Nanjing, People's Republic of China.
Shamim NematiDepartment of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.
Gari D CliffordDepartment of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.

Funding

Sleep Disturbance as a Mechanism for Ischemic Heart Disease in PTSDR01HL136205 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2017 to 2020
$3.1M
Deep Learning and Streaming Analytics for Prediction of Adverse Events in the ICUK01ES025445 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NEMATI, SHAMIM · 2015 to 2019
$951k
NHLBI NIH HHS R01 HL136205NIEHS NIH HHS K01 ES025445
6 · The paper itself

Abstract

objectiveThis study focuses on the comparison of single entropy measures for ventricular response analysis-based AF detection. APPROACH: To enhance the performance of entropy-based AF detectors, we developed a normalized fuzzy entropy, [Formula: see text], a novel metric that (1) uses a fuzzy function to determine vector similarity, (2) replaces probability estimation with density estimation for entropy approximation, (3) utilizes a flexible distance threshold parameter, and (4) adjusts for heart rate by subtracting the natural log value of the mean RR interval. An AF detector based on [Formula: see text] was trained using the MIT-BIH atrial fibrillation (AF) database, and tested on the MIT-BIH normal sinus rhythm (NSR) and MIT-BIH arrhythmia databases. The [Formula: see text]-based AF detector was compared to AF detectors based on three other entropy measures: sample entropy ([Formula: see text]), fuzzy measure entropy ([Formula: see text]) and coefficient of sample entropy ([Formula: see text]), over three standard window sizes. MAIN

resultsTo classify AF and non-AF rhythms, [Formula: see text] achieved the highest area under receiver operating characteristic curve (AUC) values of 92.72%, 95.27% and 96.76% for 12-, 30- and 60-beat window lengths respectively. This was higher than the performance of the next best technique, [Formula: see text], over all windows sizes, which provided respective AUCs of 91.12%, 91.86% and 90.55%. [Formula: see text] and [Formula: see text] resulted in lower AUCs (below 90%) over all window sizes. [Formula: see text] also provided superior performance for all other tested statistics, including the Youden index, sensitivity, specificity, accuracy, positive predictivity and negative predictivity. In conclusion, we show that [Formula: see text] can be used to accurately identify AF from RR interval time series. Furthermore, longer window lengths (up to one minute) increase the performance of all entropy-based AF detectors under evaluation except the [Formula: see text]-based method. SIGNIFICANCE: Our results demonstrate that the new developed normalized fuzzy entropy is an accurate measure for detecting AF.

Indexed as

EntropyAtrial FibrillationDatabases, FactualFuzzy LogicHeart RateHumansVentricular Dysfunction

Identifiers

PMID29897343
PMCPMC8522195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.