Evidence map›Paper›PMID 29897299›Full record

ReviewPhysiology (Bethesda, Md.)2018

Carotid Bodies and the Integrated Cardiorespiratory Response to Hypoxia.

Bruce G Lindsey, Sarah C Nuding, Lauren S Segers, Kendall F Morris

Open access · bronzeAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Testing individual baroreflex responses to hypoxia-induced peripheral chemoreflex stimulation.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020
    Trial
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  5. Review
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  13. Experimental Modeling of Damaging and Protective Hypoxia of the Mammalian Brain.Journal of evolutionary biochemistry and physiology · 2022
    Article
  14. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bruce G LindseyDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida , Tampa, Florida.
Sarah C NudingDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida , Tampa, Florida.
Lauren S SegersDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida , Tampa, Florida.
Kendall F MorrisDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida , Tampa, Florida.
University of South Florida · US

Funding

BRAINSTEM RESPIRATORY NEURON INTERACTIONSR01NS019814 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 1985 to 2015
$3.6M
Brainstem Respiratory Neuron InteractionsR37NS019814 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 2004 to 2010
$3.6M
Computational Studies of the Respiratory BrainstemR01NS046062 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 2002 to 2006
$2.1M
NINDS NIH HHS R01 NS019814NINDS NIH HHS R01 NS046062NINDS NIH HHS R37 NS019814
6 · The paper itself

Abstract

Advances in our understanding of brain mechanisms for the hypoxic ventilatory response, coordinated changes in blood pressure, and the long-term consequences of chronic intermittent hypoxia as in sleep apnea, such as hypertension and heart failure, are giving impetus to the search for therapies to "erase" dysfunctional memories distributed in the carotid bodies and central nervous system. We review current network models, open questions, sex differences, and implications for translational research.

Indexed as

Blood PressureCarotid BodyHumansHypertensionHypoxiaSex CharacteristicsSleep Apnea Syndromes

Identifiers

PMID29897299
PMCPMC6088141
OpenAlexW2808331369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.