Evidence map›Paper›PMID 29897266›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice.

Erin Wolf, Edward J Diaz, Alison N Hollis, Thien A Hoang, Hooman A Azad, Katharine M Bendt, Robert C Griffiths, Matthew A Sparks

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Evaluation of Active Renin Concentration in A Cohort of Adolescents with Primary Hypertension.International journal of environmental research and public health · 2022
    Article
  4. Angiotensin II and ATInternational journal of molecular sciences · 2022
    Review
  5. Article
  6. Vascular control of kidney epithelial transporters.American journal of physiology. Renal physiology · 2021
    Article
  7. Article
  8. Recent advances in sex differences in kidney function.American journal of physiology. Renal physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Erin WolfDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Edward J DiazDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Alison N HollisDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Thien A HoangDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Hooman A AzadDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Katharine M BendtDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Robert C GriffithsDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.
Matthew A SparksDivision of Nephrology, Department of Medicine, Duke University Medical Center , Durham, North Carolina.ORCID 0000-0003-2075-2691
Duke Medical Center · US

Funding

Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI FOSTER, MARY H., SVETKEY, LAURA P · 2012 to 2016
$5.9M
AT1 Angiotensin Receptors in the Renal Circulation Control Blood PressureIK2BX002240 · VA · DURHAM VA MEDICAL CENTER · PI SPARKS, MATTHEW AARON · 2014 to 2018
–
BLRD VA IK2 BX002240NIDDK NIH HHS P30 DK096493
6 · The paper itself

Abstract

Angiotensin II (ANG II) is a major mediator of hypertension pathogenesis. In addition, there are well-documented differences in expression of the renin-angiotensin system (RAS) components and ANG II responses between males and females, which may explain sex differences in blood pressure (BP) and hypertension epidemiology. We previously showed that type 1A angiotensin (AT

Indexed as

Angiotensin IIAnimalsBlood PressureFemaleHypertensionKidneyMaleMice, TransgenicMyocytes, Smooth MuscleNatriuresisReceptor, Angiotensin, Type 1Sex FactorsSodiumVascular ResistanceVasoconstrictor AgentsAngiotensin IIReceptor, Angiotensin, Type 1SodiumVasoconstrictor Agentsangiotensinblood pressuresex differencessodium homeostasis

Identifiers

PMID29897266
PMCPMC6230724
OpenAlexW2808071162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.