Evidence map›Paper›PMID 29896567›Full record

ArticlemSystems

Genomics of the Uncultivated, Periodontitis-Associated Bacterium

Clifford J Beall, Alisha G Campbell, Ann L Griffen, Mircea Podar, Eugene J Leys

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Omics for deciphering oral microecology.International journal of oral science · 2024
    Review
  5. Article
  6. Review
  7. The Oral Microbiome in Periodontal Health.Frontiers in cellular and infection microbiology · 2021
    Article
  8. Article
  9. Unique Features of Tandem Repeats in Bacteria.Journal of bacteriology · 2020
    Article
  10. Single-Cell Genomics and the Oral Microbiome.Journal of dental research · 2020
    Review
  11. Persistence ofCurrent oral health reports · 2020
    Article
  12. Article
  13. Oral microbial biofilms: an update.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clifford J BeallDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-2198-9124
Alisha G CampbellBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
Ann L GriffenDivision of Pediatric Dentistry, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.
Mircea PodarBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
Eugene J LeysDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.
The Ohio State University · USOak Ridge National Laboratory · US

Funding

Culturing of the uncultured: reverse genomics and multispecies consortia in oralR01DE024463 · NIDCR · UT-BATTELLE, LLC-OAK RIDGE NATIONAL LAB · PI JOULINE, IGOR B., LEYS, EUGENE J · 2014 to 2018
$8.2M
MOLECULAR &POPULATION GENETICS OF PERIODONTAL PATHOGENSR01DE010467 · NIDCR · OHIO STATE UNIVERSITY · PI LEYS, EUGENE J · 1995 to 2011
$3.4M
NIDCR NIH HHS R01 DE010467NIDCR NIH HHS R01 DE024463
6 · The paper itself

Abstract

Despite decades of research into the human oral microbiome, many species remain uncultivated. The technique of single-cell whole-genome amplification and sequencing provides a means of deriving genome sequences for species that can be informative on biological function and suggest pathways to cultivation. Tannerella forsythia has long been known to be highly associated with chronic periodontitis and to cause periodontitis-like symptoms in experimental animals, and

Indexed as

oral microbiologyperiodontitissingle cellTannerellaWGA

Identifiers

PMID29896567
PMCPMC5989130
OpenAlexW2806408431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.