Evidence map›Paper›PMID 29896198›Full record

ArticleFrontiers in immunology2018

Morphological and Functional Characterization of IL-12Rβ2 Chain on Intestinal Epithelial Cells: Implications for Local and Systemic Immunoregulation.

Mari Regoli, Angela Man, Nadhezda Gicheva, Antonio Dumont, Kamal Ivory, Alessandra Pacini, Gabriele Morucci, Jacopo J V Branca, Monica Lucattelli, Ugo Santosuosso and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Mari RegoliDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Angela ManGut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Nadhezda GichevaGut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Antonio DumontEuropean Food Safety Authority, EFSA, Parma, Italy.
Kamal IvoryGut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Alessandra PaciniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Gabriele MorucciDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Jacopo J V BrancaDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Monica LucattelliDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Ugo SantosuossoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Arjan NarbadGut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Massimo GulisanoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Eugenio BertelliDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Claudio NicolettiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
University of Florence · ITQuadram Institute · GBUniversity of Siena · ITEuropean Food Safety Authority · IT

Funding

Biotechnology and Biological Sciences Research Council BB/J004529/1Biotechnology and Biological Sciences Research Council BBS/E/F/00044453Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10356
6 · The paper itself

Abstract

Interaction between intestinal epithelial cells (IECs) and the underlying immune systems is critical for maintaining intestinal immune homeostasis and mounting appropriate immune responses. We have previously showed that the T helper type 1 (T

Indexed as

Immunity, MucosalModels, ImmunologicalAnimalsCoculture TechniquesEpithelial CellsFood HypersensitivityInterleukin-12Intestinal MucosaLactococcus lactisMiceMice, KnockoutReceptors, Interleukin-12Il12rb2 protein, mouseInterleukin-12Receptors, Interleukin-12IL12Rβ2 chainimmunoregulationinterleukin 12intestinal epithelial cellmucosal immunity

Identifiers

PMID29896198
PMCPMC5986899
OpenAlexW2800524128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.