Trial reportScientific reports2018
Exploring the Relationship between Blood Flux Signals and HRV following Different Thermal Stimulations using Complexity Analysis.
Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Trial
- Photobiomodulation combined with dynamic thermal imaging as a diagnostic tool for chronic leg ulcers.Lasers in medical science · 2026Article
- A comparative metabolomics study between grain-sized moxibustion and suspended moxibustion on rats with gastric ulcers.Heliyon · 2023Article
- The Relationship Between Blood Perfusion in the Lower Extremities and Heart Rate Variability at Different Positions.Frontiers in physiology · 2021Article
- Pilot Study of Blood Perfusion Changes at PC4 and Its Surrounding Points Induced by Acupuncture and Moxibustion.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Impact of local thermal stimulation on the correlation between oxygen saturation and speed-resolved blood perfusion.Scientific reports · 2020Article
- Dysregulated Neurovascular Control Underlies Declining Microvascular Functionality in People With Non-alcoholic Fatty Liver Disease (NAFLD) at Risk of Liver Fibrosis.Frontiers in physiology · 2020Article
- Enhanced flow-motion complexity of skin microvascular perfusion in Sherpas and lowlanders during ascent to high altitude.Scientific reports · 2019Article
- The Effect of Moxibustion Stimulation on Local and Distal Skin Temperature in Healthy Subjects.Evidence-based complementary and alternative medicine : eCAM · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the relationship between local blood flux and heart rate variability following different thermal stimulations, healthy subjects were recruited and subject to different thermal stimulations on the right forearm. Multiscale entropy and multiscale fuzzy entropy were used to measure the complexity of the local blood flux, and the approximate entropy was calculated to evaluate the HRV complexity. The results indicated that thermal stimulation significantly increased local blood flux and that different temperature stimulations resulted in different complexities in local blood flux. A 42 °C or 44 °C thermal stimulation, other than stimulations below 42 °C, resulted in a moderate correlation between local blood flux and heart rate variability complexity. The results provide a new perspective in terms of complexity to explore the relationship between skin blood flux signals and cardiac function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.