Evidence map›Paper›PMID 29895966›Full record

ArticleScientific reports2018

A Dual-Modality Hybrid Imaging System Harnesses Radioluminescence and Sound to Reveal Molecular Pathology of Atherosclerotic Plaques.

Raiyan T Zaman, Siavash Yousefi, Steven R Long, Toshinobu Saito, Michael Mandella, Zhen Qiu, Ruimin Chen, Christopher H Contag, Sanjiv S Gambhir, Frederick T Chin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. In Vivo Translation of the CIRPI System: Revealing Molecular Pathology of Rabbit Aortic Atherosclerotic Plaques.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Raiyan T ZamanDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, USA. rtzaman@stanford.edu.
Siavash YousefiDivision of Medical Physics, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Steven R LongDepartment of Pathology, Stanford University School of Medicine, Stanford, USA.
Toshinobu SaitoDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, USA.
Michael MandellaDepartment of Pediatrics (Neonatology), Stanford University School of Medicine, Stanford, USA.
Zhen QiuDepartment of Radiology, Stanford University School of Medicine, Stanford, USA.
Ruimin ChenDepartment of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Stanford, USA.ORCID 0000-0002-5338-359X
Christopher H ContagDepartment of Pediatrics (Neonatology), Stanford University School of Medicine, Stanford, USA.ORCID 0000-0002-1011-8278
Sanjiv S GambhirDepartment of Radiology, Stanford University School of Medicine, Stanford, USA.
Frederick T ChinDepartment of Radiology, Stanford University School of Medicine, Stanford, USA.
Butras T Khuri-YakubDepartment of Electrical Engineering, Stanford University, Stanford, USA.
Michael V McConnellDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, USA.
K Kirk ShungDepartment of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Stanford, USA.
Lei XingDivision of Medical Physics, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Stanford University · USStanford Medicine · USUniversity of Southern California · USHarvard University · USMichigan State University · US

Funding

STANFORD CANCER IMAGING TRAINING (SCIT) PROGRAMT32CA009695 · NCI · STANFORD UNIVERSITY · PI BRUCE L DANIEL, Jeremy Dahl · 1993 to 2026
$7.7M
A Novel Intravascular CRI-PAT Imaging System to Characterize Vulnerable PlaqueR00HL127180 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ZAMAN, RAIYAN TRIPTI · 2019 to 2021
$745k
Vevo LAZR Photoacoustic and Ultrasound Imaging SystemS10OD010344 · OD · STANFORD UNIVERSITY · PI GAMBHIR, SANJIV S · 2013 to 2013
$522k
A Novel Intravascular CRI-PAT Imaging System to Characterize Vulnerable PlaqueK99HL127180 · NHLBI · STANFORD UNIVERSITY · PI ZAMAN, RAIYAN TRIPTI · 2015 to 2016
$279k
NCI NIH HHS T32 CA009695NHLBI NIH HHS K99 HL127180NHLBI NIH HHS R00 HL127180NIH HHS S10 OD010344
6 · The paper itself

Abstract

Atherosclerosis is a progressive inflammatory condition caused by an unstable lesion, called thin-cap fibro atheromata (TCFA) that underlies coronary artery disease (CAD)-one of the leading causes of death worldwide. Therefore, early clinical diagnosis and effective risk stratification is important for CAD management as well as preventing progression to catastrophic events. However, early detection could be difficult due to their small size, motion, obscuring

Indexed as

AutoradiographyLuminescent MeasurementsMultimodal ImagingPhotoacoustic TechniquesAnimalsCarotid ArteriesCarotid Artery DiseasesCoronary Artery DiseaseFluorodeoxyglucose F18HumansMicePlaque, AtheroscleroticFluorodeoxyglucose F18

Identifiers

PMID29895966
PMCPMC5997702
OpenAlexW2805672827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.