Evidence map›Paper›PMID 29895744›Full record

ArticleMolecules (Basel, Switzerland)2018

Novel Thiazolidinone/Thiazolo[3,2-

Mohamed El-Naggar, Wagdy M Eldehna, Hadia Almahli, Amr Elgez, Mohamed Fares, Mahmoud M Elaasser, Hatem A Abdel-Aziz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
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  8. Design, synthesis,RSC advances · 2025
    Article
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  12. Review
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  14. 4-Thiazolidinone-Bearing Hybrid Molecules in Anticancer Drug Design.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Mohamed El-NaggarChemistry Department, Faculty of Sciences, University of Sharjah, Sharjah 27272, UAE. m5elnaggar@yahoo.com.
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. wagdy2000@gmail.com.
Hadia AlmahliChemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA Oxford, UK. hadia.almahli@yahoo.com.
Amr ElgezDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 11829, Egypt. amro_elgez@yahoo.com.ORCID 0000-0002-7857-419X
Mohamed FaresDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 11829, Egypt. ph.fares@yahoo.com.
Mahmoud M ElaasserThe Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo 11759, Egypt. mmelaasser@hotmail.com.ORCID 0000-0003-0862-7628
Hatem A Abdel-AzizDepartment of Applied Organic Chemistry, National Research Center, Dokki, Cairo 12622, Egypt. hatem_741@yahoo.com.
Al-Azhar University · EGEgyptian Russian University · EGKafrelsheikh University · EGNational Research Centre · EGUniversity of Oxford · GBUniversity of Sharjah · AEUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In connection with our research program on the development of new isatin-based anticancer candidates, herein we report the synthesis of two novel series of thiazolidinone-isatin conjugates (

Indexed as

Antineoplastic Agentsbcl-2-Associated X ProteinBenzimidazolesCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorFemaleGene Expression Regulation, NeoplasticHeterocyclic Compounds, 2-RingHumansIn Vitro TechniquesIsatinMCF-7 CellsMolecular StructureProto-Oncogene Proteins c-bcl-2Antineoplastic AgentsBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanBenzimidazolesHeterocyclic Compounds, 2-RingIsatinProto-Oncogene Proteins c-bcl-2anticancerapoptosisisatin-thiazolidinone hybridsQSARtriple-negative breast cancer

Identifiers

PMID29895744
PMCPMC6099623
OpenAlexW2808522316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.