Evidence map›Paper›PMID 29895681›Full record

ArticleThe Journal of experimental biology2018

Cardiac mitochondrial metabolism may contribute to differences in thermal tolerance of red- and white-blooded Antarctic notothenioid fishes.

Kristin M O'Brien, Anna S Rix, Stuart Egginton, Anthony P Farrell, Elizabeth L Crockett, Karen Schlauch, Rebekah Woolsey, Megan Hoffman, Sean Merriman

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of experimental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Characterization of darter (Conservation physiology · 2025
    Article
  3. Article
  4. A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022
    Article
  5. Article
  6. Proteomic analysis of the ATP synthase interactome in notothenioids highlights a pathway that inhibits ceruloplasmin production.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Characterization of the hypoxia-inducible factor-1 pathway in hearts of Antarctic notothenioid fishes.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology · 2020
    Article
  15. Mitochondrial membranes in cardiac muscle from Antarctic notothenioid fishes vary in phospholipid composition and membrane fluidity.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology · 2019
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Kristin M O'BrienInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA kmobrien@alaska.edu.ORCID 0000-0002-3311-0690
Anna S RixInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA.
Stuart EggintonSchool of Biomedical Sciences, University of Leeds, Leeds LS2 9JT, UK.
Anthony P FarrellDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4.
Elizabeth L CrockettDepartment of Biological Sciences, Ohio University, Athens, OH 45701, USA.
Karen SchlauchDepartment of Biochemistry and Molecular Biology, University of Nevada, Reno, NV 89557, USA.
Rebekah WoolseyNevada Proteomics Center, University of Nevada, Reno, NV 89557, USA.
Megan HoffmanInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA.
Sean MerrimanInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA.
University of Alaska Fairbanks · USUniversity of Nevada, Reno · USOhio University · USUniversity of British Columbia · CAUniversity of Leeds · GB

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Outreach/Diversity/Pipeline ProjectP20GM103440 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Julia Petereit · 2012 to 2026
$58.0M
NIGMS NIH HHS P20 GM103395NIGMS NIH HHS P20 GM103440
6 · The paper itself

Abstract

Studies in temperate fishes provide evidence that cardiac mitochondrial function and the capacity to fuel cardiac work contribute to thermal tolerance. Here, we tested the hypothesis that decreased cardiac aerobic metabolic capacity contributes to the lower thermal tolerance of the haemoglobinless Antarctic icefish,

Indexed as

Hot TemperatureAdenosine TriphosphateAnimalsAntarctic RegionsCitrate (si)-SynthaseL-Lactate DehydrogenaseMitochondria, HeartMyocardiumPerciformesAdenosine TriphosphateCitrate (si)-SynthaseL-Lactate DehydrogenaseAerobic metabolismAntarctic fishCardiac muscleMitochondria

Identifiers

PMID29895681
PMCPMC6104818
OpenAlexW2808014816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.