Evidence map›Paper›PMID 29895677›Full record

ArticleRNA (New York, N.Y.)2018

Microprocessor-dependent processing of splice site overlapping microRNA exons does not result in changes in alternative splicing.

Giulia Pianigiani, Danilo Licastro, Paola Fortugno, Daniele Castiglia, Ivana Petrovic, Franco Pagani

Open access · hybridAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. IFN-I inducibleFrontiers in immunology · 2022
    Article
  6. Review
  7. Review
  8. Are spliced ncRNA host genes distinct classes of lncRNAs?Theory in biosciences = Theorie in den Biowissenschaften · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Giulia PianigianiHuman Molecular Genetics, International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.ORCID 0000-0003-0851-1473
Danilo LicastroCBM S.c.r.l., Area Science Park, Basovizza, 34149 Trieste, Italy.
Paola FortugnoLaboratory of Molecular and Cell Biology, Istituto Dermopatico dell'Immacolata (IDI)-IRCCS, 00167 Rome, Italy.
Daniele CastigliaLaboratory of Molecular and Cell Biology, Istituto Dermopatico dell'Immacolata (IDI)-IRCCS, 00167 Rome, Italy.
Ivana PetrovicHuman Molecular Genetics, International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.
Franco PaganiHuman Molecular Genetics, International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.
International Centre for Genetic Engineering and Biotechnology · ITIstituto Dermopatico dell'Immacolata · ITAREA Science Park · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs are found throughout the genome and are processed by the microprocessor complex (MPC) from longer precursors. Some precursor miRNAs overlap intron:exon junctions. These

Indexed as

RNA Splice SitesAlternative SplicingCell DifferentiationCell ProliferationCells, CulturedChromatinDown-RegulationExonsGene SilencingHumansKeratinocytesMicroRNAsPhosphoproteinsRibonuclease IIIRNA Splicing FactorsSpliceosomesChromatinDROSHA protein, humanMicroRNAsPhosphoproteinsRibonuclease IIIRNA Splice SitesRNA Splicing FactorsSF3B1 protein, humanmicroprocessor complexsmall RNA-seqsplice site overlapping miRNAsplicing, keratinocytes

Identifiers

PMID29895677
PMCPMC6097652
OpenAlexW2807899041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.