Evidence map›Paper›PMID 29895642›Full record

ArticlemBio2018

Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of

Sanjiv Kumar, Melissa J Caimano, Arvind Anand, Abhishek Dey, Kelly L Hawley, Morgan E LeDoyt, Carson J La Vake, Adriana R Cruz, Lady G Ramirez, Lenka Paštěková and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 42 citations in OpenAlex.

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  14. Genetic Profiling of the Full-LengthMicrobiology spectrum · 2023
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  20. Mosaic Evolution of Beta-Barrel-Porin-Encoding Genes inApplied and environmental microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Sanjiv Kumar *Department of Medicine, UConn Health, Farmington, Connecticut, USA.
Melissa J Caimano *Department of Medicine, UConn Health, Farmington, Connecticut, USA.
Arvind AnandDepartment of Medicine, UConn Health, Farmington, Connecticut, USA.
Abhishek DeyDepartment of Medicine, UConn Health, Farmington, Connecticut, USA.
Kelly L HawleyDepartment of Pediatrics, UConn Health, Farmington, Connecticut, USA.
Morgan E LeDoytDepartment of Medicine, UConn Health, Farmington, Connecticut, USA.
Carson J La VakeDepartment of Pediatrics, UConn Health, Farmington, Connecticut, USA.
Adriana R CruzCentro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Colombia.
Lady G RamirezCentro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Colombia.
Lenka PaštěkováDepartment of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Irina BezsonovaDepartment of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, USA.
David ŠmajsDepartment of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Juan C SalazarDepartment of Pediatrics, UConn Health, Farmington, Connecticut, USA.
Justin D RadolfDepartment of Medicine, UConn Health, Farmington, Connecticut, USA JRadolf@uchc.edu.
UConn Health · USCentro Internacional de Entrenamiento e Investigaciones Medicas · COMasaryk University · CZConnecticut Children's Medical Center · US

Funding

RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
Treponema pallidum Outer Membrane Proteins and Transition Metal AcquisitionR01AI026756 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI RADOLF, JUSTIN D · 1992 to 2017
$5.1M
T.pallidum Membrane Immunogens and Anti-Oxidant DefenseR37AI026756 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2002 to 2006
$1.8M
Identification of genes required by Leptospira interrogans for mammalian host adaptation and/or persistence in the rat modelR21AI128379 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CAIMANO, MELISSA J · 2017 to 2018
$439k
Mechanisms of Immune Evasion and Recognition in Human SyphilisR03TW009172 · FIC · CENTRO INTERNACIONAL (CIDEIM) · PI CRUZ, ADRIANA RAQUEL · 2013 to 2015
$142k
FIC NIH HHS R03 TW009172NIAID NIH HHS R01 AI026756NIAID NIH HHS R01 AI029735NIAID NIH HHS R37 AI026756
6 · The paper itself

Abstract

In recent years, considerable progress has been made in topologically and functionally characterizing integral outer membrane proteins (OMPs) of

Indexed as

Evolution, MolecularAmino Acid SequenceBacterial Outer Membrane ProteinsBase SequenceFemaleGenetic VariationHumansMaleMolecular Sequence DataPhylogenyProtein DomainsSequence AlignmentSpirochaetalesSyphilisTreponema pallidumBacterial Outer Membrane Proteinsmolecular subtypingouter membrane proteinsspirochetessyphilisTreponema pallidum

Identifiers

PMID29895642
PMCPMC6016234
OpenAlexW2802269688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.