Evidence map›Paper›PMID 29895620›Full record

ArticleThe Journal of biological chemistry2018

Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in

Clélia Bourgoint, Delphine Rispal, Marina Berti, Ireos Filipuzzi, Stephen B Helliwell, Manoël Prouteau, Robbie Loewith

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  9. HJournal of fungi (Basel, Switzerland) · 2021
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  15. Review
  16. Applied and environmental microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Clélia BourgointDepartment of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), National Center for Competence in Research in Chemical Biology, University of Geneva, 1211 Geneva, Switzerland.
Delphine RispalDepartment of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), National Center for Competence in Research in Chemical Biology, University of Geneva, 1211 Geneva, Switzerland.
Marina BertiDepartment of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), National Center for Competence in Research in Chemical Biology, University of Geneva, 1211 Geneva, Switzerland.
Ireos FilipuzziNovartis Institutes for Biomedical Research, Novartis Campus, 4056 Basel, Switzerland.
Stephen B HelliwellNovartis Institutes for Biomedical Research, Novartis Campus, 4056 Basel, Switzerland.
Manoël ProuteauDepartment of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), National Center for Competence in Research in Chemical Biology, University of Geneva, 1211 Geneva, Switzerland. Electronic address: manoel.prouteau@unige.ch.
Robbie LoewithDepartment of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), National Center for Competence in Research in Chemical Biology, University of Geneva, 1211 Geneva, Switzerland. Electronic address: robbie.loewith@unige.ch.
University of Geneva · CHNovartis (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Target of rapamycin complex 2 (TORC2) is a widely conserved serine/threonine protein kinase. In the yeast

Indexed as

Gene Expression Regulation, FungalActin CytoskeletonCell MembraneEndocytosisGlycerolGlycogen Synthase Kinase 3Mechanistic Target of Rapamycin Complex 2Microfilament ProteinsPhosphorylationProtein Kinase InhibitorsProtein KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSerineSignal TransductionSphingolipidsFpk1 protein, S cerevisiaeFpk2 protein, S cerevisiaeGlycerolGlycogen Synthase Kinase 3MCK1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 2Microfilament ProteinsPAN1 protein, S cerevisiaeProtein Kinase InhibitorsProtein KinasesSaccharomyces cerevisiae ProteinsSerineSphingolipidsactinaminophospholipid flippaseArk1/Prk1 familyendocytosisFpk1in vitro kinase assaymembrane functionPan1signal transductiontarget of rapamycin (TOR)

Identifiers

PMID29895620
PMCPMC6078453
OpenAlexW2807739971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.