Evidence map›Paper›PMID 29895618›Full record

ArticleThe Journal of biological chemistry2018

The crystal structure of the

Christopher J Hosford, Joshua S Chappie

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Rapid Detection ofACS omega · 2021
    Article
  3. Article
  4. The structure of theThe Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher J HosfordFrom the Department of Molecular Medicine, Cornell University, Ithaca, New York 14853.
Joshua S ChappieFrom the Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 chappie@cornell.edu.ORCID 0000-0002-5733-7275
Cornell University · US

Funding

Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
Structural and Functional Characterization of the McrBC Restriction SystemR01GM120242 · NIGMS · CORNELL UNIVERSITY · PI CHAPPIE, JOSHUA S · 2018 to 2022
$1.8M
NCRR NIH HHS S10 RR029205NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R01 GM120242
6 · The paper itself

Abstract

Restriction modification systems consist of an endonuclease that cleaves foreign DNA site-specifically and an associated methyltransferase that protects the corresponding target site in the host genome. Modification-dependent restriction systems, in contrast, specifically recognize and cleave methylated and/or glucosylated DNA. The LlaJI restriction system contains two 5-methylcytosine (5mC) methyltransferases (LlaJI.M1 and LlaJI.M2) and two restriction proteins (LlaJI.R1 and LlaJI.R2). LlaJI.R1 and LlaJI.R2 are homologs of McrB and McrC, respectively, which in

Indexed as

Bacterial ProteinsBinding SitesCrystallography, X-RayDNADNA Restriction-Modification EnzymesHelicobacter InfectionsHelicobacter pyloriModels, MolecularProtein BindingProtein ConformationProtein DomainsBacterial ProteinsDNADNA Restriction-Modification EnzymesDNA binding proteinDNA endonucleaseDNA enzymeprotein structurerestriction systemX-ray crystallography

Identifiers

PMID29895618
PMCPMC6066307
OpenAlexW2808086390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.