Evidence map›Paper›PMID 29895617›Full record

ArticleScience signaling2018

Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity.

Jonathan S Duke-Cohan, Yuki Ishikawa, Akihiro Yoshizawa, Young-Il Choi, Chin-Nien Lee, Oreste Acuto, Stephan Kissler, Ellis L Reinherz

Open access · greenAbstract read
In one paragraph

Article in Science signaling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Thymus and autoimmunity.Seminars in immunopathology · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jonathan S Duke-CohanLaboratory of Immunobiology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. ellis_reinherz@dfci.harvard.edu jonathan_duke-cohan@dfci.harvard.edu stephan.kissler@joslin.harvard.edu.ORCID 0000-0002-9478-9609
Yuki IshikawaDepartment of Medicine, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-6514-8239
Akihiro YoshizawaLaboratory of Immunobiology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.ORCID 0000-0001-9941-6038
Young-Il ChoiLaboratory of Immunobiology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.ORCID 0000-0002-5598-4292
Chin-Nien LeeDepartment of Medicine, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-9655-622X
Oreste AcutoSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Stephan KisslerDepartment of Medicine, Harvard Medical School, Boston, MA 02115, USA. ellis_reinherz@dfci.harvard.edu jonathan_duke-cohan@dfci.harvard.edu stephan.kissler@joslin.harvard.edu.ORCID 0000-0003-3062-7800
Ellis L ReinherzLaboratory of Immunobiology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. ellis_reinherz@dfci.harvard.edu jonathan_duke-cohan@dfci.harvard.edu stephan.kissler@joslin.harvard.edu.ORCID 0000-0003-1048-5526
Harvard University · USJoslin Diabetes Center · USUniversity of Oxford · GB

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Thymocyte integrin regulation by plexinD1R01AI115698 · NIAID · DANA-FARBER CANCER INST · PI REINHERZ, ELLIS L · 2015 to 2018
$1.7M
Special BD LSRFortessaS10OD021740 · OD · JOSLIN DIABETES CENTER · PI SERWOLD, THOMAS F · 2016 to 2016
$363k
NIAID NIH HHS R01 AI115698NIDDK NIH HHS P30 DK036836NIH HHS S10 OD021740Wellcome TrustWellcome Trust WT094296MA
6 · The paper itself

Abstract

Multiple autoimmune pathologies are associated with single-nucleotide polymorphisms of the human gene

Indexed as

AnimalsAutoimmune DiseasesCell AdhesionCell MovementCytoskeletal ProteinsFemaleGlycoproteinsGTPase-Activating ProteinsHumansIntegrinsIntracellular Signaling Peptides and ProteinsMaleMembrane GlycoproteinsMembrane ProteinsMiceMice, Inbred C57BLCytoskeletal ProteinsGlycoproteinsGTPase-Activating ProteinsIntegrinsIntracellular Signaling Peptides and ProteinsMembrane GlycoproteinsMembrane ProteinsNerve Tissue ProteinsPlxnd1 protein, mouserhoA GTP-Binding ProteinRNA, Small InterferingSema3e protein, mouseSemaphorinsTAGAP protein, mouse

Identifiers

PMID29895617
PMCPMC6393939
OpenAlexW2808562319

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.