Evidence map›Paper›PMID 29895593›Full record

SynthesisDiabetes2018

The Common

Jonathan M Locke, Cécile Saint-Martin, Thomas W Laver, Kashyap A Patel, Andrew R Wood, Seth A Sharp, Sian Ellard, Christine Bellanné-Chantelot, Andrew T Hattersley, Lorna W Harries and 1 more

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Biomedical reports · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Variants influencing age at diagnosis of HNF1A-MODY.Molecular medicine (Cambridge, Mass.) · 2022
    Article
  9. HNF1A Mutations and Beta Cell Dysfunction in Diabetes.International journal of molecular sciences · 2022
    Review
  10. First Japanese Family WithJournal of the Endocrine Society · 2022
    Article
  11. Maturity Onset Diabetes of the Young-New Approaches for Disease Modelling.International journal of molecular sciences · 2021
    Review
  12. NGS Analysis Revealed Digenic HeterozygousDiagnostics (Basel, Switzerland) · 2021
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jonathan M LockeInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K. j.locke@exeter.ac.uk.ORCID 0000-0001-9516-5251
Cécile Saint-MartinDepartment of Genetics, Pitié-Salpétrière Hospital, Assistance Publique-Hôpitaux de Paris, and Pierre et Marie Curie University, Paris, France.
Thomas W LaverInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.ORCID 0000-0001-6399-0089
Kashyap A PatelInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.ORCID 0000-0002-9240-8104
Andrew R WoodInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Seth A SharpInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Sian EllardInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Christine Bellanné-ChantelotDepartment of Genetics, Pitié-Salpétrière Hospital, Assistance Publique-Hôpitaux de Paris, and Pierre et Marie Curie University, Paris, France.
Andrew T HattersleyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.ORCID 0000-0001-5620-473X
Lorna W HarriesInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Michael N WeedonInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, U.K.
University of Exeter · GBSorbonne Université · FR

Funding

Medical Research Council MR/J006777/1Medical Research Council MR/M005070/1Medical Research Council MR/M00507/1
6 · The paper itself

Abstract

There is wide variation in the age at diagnosis of diabetes in individuals with maturity-onset diabetes of the young (MODY) due to a mutation in the

Indexed as

Genetic Predisposition to DiseaseMutation, MissensePolymorphism, Single NucleotideAge of OnsetAllelesAmino Acid SubstitutionCohort StudiesDatabases, GeneticDiabetes Mellitus, Type 2DNA Mutational AnalysisEnglandFemaleGene FrequencyGenetic Association StudiesGenome-Wide Association StudyHepatocyte Nuclear Factor 1-alphaHepatocyte Nuclear Factor 1-alphaHNF1A protein, human

Identifiers

PMID29895593
PMCPMC6109380
OpenAlexW2808145804

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.