Evidence map›Paper›PMID 29895299›Full record

ArticleCardiovascular diabetology2018

Association between abdominal adiposity and subclinical measures of left-ventricular remodeling in diabetics, prediabetics and normal controls without history of cardiovascular disease as measured by magnetic resonance imaging: results from the KORA-FF4 Study.

Christopher L Schlett, Roberto Lorbeer, Carolyn Arndt, Sigrid Auweter, Jürgen Machann, Holger Hetterich, Birgit Linkohr, Wolfgang Rathmann, Annette Peters, Fabian Bamberg

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular diabetology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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  15. Association of antecedent cardiovascular risk factor levels and trajectories with cardiovascular magnetic resonance-derived cardiac function and structure.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Christopher L SchlettDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Roberto LorbeerInstitute of Clinical Radiology, Ludwig-Maximilian-University Hospital, Munich, Germany.
Carolyn ArndtDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Sigrid AuweterInstitute of Clinical Radiology, Ludwig-Maximilian-University Hospital, Munich, Germany.
Jürgen MachannDepartment of Diagnostic and Interventional Radiology, University of Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Holger HetterichInstitute of Clinical Radiology, Ludwig-Maximilian-University Hospital, Munich, Germany.
Birgit LinkohrInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Wolfgang RathmannDepartment of Biometry and Epidemiology, German Diabetes Center, Duesseldorf, Germany.
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Fabian BambergInstitute of Clinical Radiology, Ludwig-Maximilian-University Hospital, Munich, Germany. fabian.bamberg@uni-tuebingen.de.
Ludwig-Maximilians-Universität München · DEHeidelberg University · DEDeutsches Diabetes-Zentrum e.V. · DEHelmholtz Zentrum München · DEUniversity of Tübingen · DEZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLocal, abdominal fat depots may be related to alterations in cardiac function and morphology due to a metabolic linkage. Thus, we aimed to determine their association with subtle cardiac changes and the potential interaction with hyperglycemic metabolic states.

methodsSubjects from the general population and without history of cardiovascular disease were drawn from the Cooperative Health Research in the Region of Augsburg FF4 cohort and underwent 3 T cardiac and body MRI. Measures of abdominal adiposity such as hepatic proton-density fat fraction [PDFF

resultsAmong a total of 374 subjects (56.2 ± 9.1 years, 58% males), 49 subjects had diabetes, 99 subjects had prediabetes and 226 represented normal controls. Only subtle cardiac alterations were observed (e.g. LVCI: 1.13 ± 0.30). While SAT was not associated, increasing VAT and increasing PDFF

conclusionIn a healthy population, VAT but also PDFF

Indexed as

AdiposityMagnetic Resonance ImagingVentricular Function, LeftVentricular RemodelingAgedAsymptomatic DiseasesBiomarkersBlood GlucoseCase-Control StudiesCross-Sectional StudiesFatty LiverFemaleHumansHypertrophy, Left VentricularIntra-Abdominal FatMaleBiomarkersBlood GlucoseDiabetes mellitusFatty liverIntra-abdominal fatMagnetic resonance imagingVentricular remodeling

Identifiers

PMID29895299
PMCPMC5998572
OpenAlexW2808383304

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.