Evidence map›Paper›PMID 29894389›Full record

ArticleAIDS (London, England)2018

Antiretroviral therapy coverage associated with increased co-residence between older and working-age adults in Africa.

Jan-Walter De Neve, Omar Karlsson, Lelani Coetzee, Henning Schröder, S V Subramanian, Till Bärnighausen, Sebastian Vollmer

Abstract read
In one paragraph

Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jan-Walter De NeveInstitute of Public Health, Heidelberg University, Im Neuenheimer Feld 130.3, Heidelberg, Germany.
Omar KarlssonCentre for Economic Demography.
Lelani CoetzeeDepartment of Economics, University of Göttingen, Waldweg, Göttingen, Germany.
Henning SchröderInstitute of Public Health, Heidelberg University, Im Neuenheimer Feld 130.3, Heidelberg, Germany.
S V SubramanianDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston.
Till BärnighausenInstitute of Public Health, Heidelberg University, Im Neuenheimer Feld 130.3, Heidelberg, Germany.
Sebastian VollmerDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Funding

SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI LISA F BERKMAN · 2013 to 2026
$37.3M
Training Tanzanian Researchers for HIV/AIDS Implementation ScienceD43TW009775 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, Christopher Sudfeld · 2015 to 2026
$3.0M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
Causal Pathways to population health impact of HIV antiretroviral treatmentR01HD084233 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2015 to 2021
$2.3M
Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South AfricaR01AI124389 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2016 to 2020
$2.1M
FIC NIH HHS D43 TW009775NIAID NIH HHS R01 AI112339NIAID NIH HHS R01 AI124389NIA NIH HHS P01 AG041710NICHD NIH HHS R01 HD084233Wellcome Trust
6 · The paper itself

Abstract

objectivesTo determine whether national antiretroviral therapy (ART) coverage is associated with changes in the living arrangements of older adults.

designRetrospective analysis using 103 nationally representative surveys from 28 African countries between 1991 and 2015.

methodsThe sample consisted of individuals aged at least 60 years. We investigated how three measures of living arrangements of older adults have changed with ART coverage: the number of older individuals living without working-age adults, the number of older individuals living with only dependent children (i.e. 'missing generation' households), and the number of working-age adults per household where an older individual lives.

resultsOur sample consisted of 297 331 older adults. An increase in ART coverage of 1% was associated with a 0.7 percentage point reduction (P < 0.001) in the probability of an older adult living without working-age adult and a 0.2 percentage point reduction (P = 0.005) in the probability of an older adult living in a 'missing generation' household. Increases in ART coverage were also associated with more working-age adults in households with at least one older adult. In our study countries, representing 75% (749 million) of the sub-Saharan population, an additional 103 000-358 000 older adults could be living with working-age adults as a result of increased ART coverage (1%).

conclusionThe scale-up of ART has likely led to substantial increases in co-residence between older and working-age adults in Africa. Returns to investments in HIV treatment will be too low, if the social benefits from these changes in living arrangements of older adults are not taken into account.

Indexed as

Antiretroviral Therapy, Highly ActiveResidence CharacteristicsAdolescentAdultAfricaAgedAged, 80 and overAnti-Retroviral AgentsDrug UtilizationFemaleHumansMaleMiddle AgedRetrospective StudiesSurveys and QuestionnairesYoung AdultAnti-Retroviral Agents

Identifiers

PMID29894389
PMCPMC7293712

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.