Evidence map›Paper›PMID 29894208›Full record

ArticleBrain injury2018

Does a regular Wessex Head Injury Matrix assessment identify early signs of infections in people with Prolonged Disorders of Consciousness?

Samira Kashinath Dhamapurkar, Barbara A Wilson, Anita Rose, Gerhard Florschutz, Peter Watson, Agnes Shiel

Open access · greenAbstract read
In one paragraph

Article in Brain injury, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Behavioral scales variability in patients with prolonged disorders of consciousness.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Samira Kashinath Dhamapurkara OT Department , The Raphael Hospital , Kent , Tonbridge , UK.
Barbara A Wilsona OT Department , The Raphael Hospital , Kent , Tonbridge , UK.
Anita Rosea OT Department , The Raphael Hospital , Kent , Tonbridge , UK.
Gerhard Florschutza OT Department , The Raphael Hospital , Kent , Tonbridge , UK.
Peter Watsonc MRC Cognition and Brain Sciences Unit , Cambridgeshire , Cambridge , UK.
Agnes Shield OT Department , The National University of Ireland , Ireland , Galway.
Tonbridge School · GBMRC Cognition and Brain Sciences Unit · GBOllscoil na Gaillimhe – University of Galway · IE

Funding

Medical Research Council MC_U105579212Medical Research Council MC_U105580448Medical Research Council MC_UU_00005/14Medical Research Council MC_UU_00005/6
6 · The paper itself

Abstract

BACKGROUND &

objectivePatients with brain injury are at high risk for infections. Although infection and cognitive deterioration are established for people with dementia, this has not been shown for patients with a prolonged disorder of consciousness (PDOC). This study determines whether regular Wessex Head Injury Matrix (WHIM) assessments can identify early signs of infections in patients with PDOC.

methodRetrospective and prospective approaches were used to assess the WHIM scores of patients with a PDOC (N = 21 in the retrospective study and 22 in the prospective study).

resultsThe WHIM total scores decreased due to infections in 17 of the 21 cases of infection (p < 0.001) in the retrospective study and 15 (p = 0.001) of the 22 prospective cases of infection. Patients in a minimally conscious state (MCS) showed a bigger proportion of change between their baseline score and the scores taken in the pre-infection stage in both the retrospective and prospective studies when compared to patients in a vegetative state (VS).

conclusionThe findings suggest the importance of serial WHIM assessments throughout the period of recovery, not only to measure cognitive changes but also to highlight underlying physical changes such as infections that will impact the response to rehabilitation and recovery.

Indexed as

AdultAgedCognition DisordersConsciousness DisordersCraniocerebral TraumaFemaleHumansInfectionsMaleMiddle AgedNeurologic ExaminationNeuropsychological TestsPersistent Vegetative StateProspective StudiesRetrospective StudiesStatistics, NonparametricInfectionProlonged Disorders of Consciousness (PDOC)Wessex Head Injury Matrix (WHIM)

Identifiers

PMID29894208
PMCPMC6717515
OpenAlexW2808025205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.