Evidence map›Paper›PMID 29893864›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2018

Opportunities and challenges in developing deep learning models using electronic health records data: a systematic review.

Cao Xiao, Edward Choi, Jimeng Sun

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 259 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
259citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

259 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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199 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cao XiaoAI for Healthcare, IBM Research, Cambridge, Massachusetts, USA.
Edward ChoiSchool of Computational Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Jimeng SunSchool of Computational Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.

Funding

Reducing Disparities among Kidney Transplant RecipientsR01MD011682 · NIMHD · EMORY UNIVERSITY · PI ADAMS, ANDREW B, PATZER, RACHEL E · 2017 to 2021
$2.4M
Interpretable Deep Learning Model for Longitudinal Electronic Health Records and Applications to Heart Failure PredictionR56HL138415 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI ZHANG, CHAO · 2017 to 2017
$756k
NHLBI NIH HHS R56 HL138415NIMHD NIH HHS R01 MD011682
6 · The paper itself

Abstract

Objective: To conduct a systematic review of deep learning models for electronic health record (EHR) data, and illustrate various deep learning architectures for analyzing different data sources and their target applications. We also highlight ongoing research and identify open challenges in building deep learning models of EHRs. Design/method: We searched PubMed and Google Scholar for papers on deep learning studies using EHR data published between January 1, 2010, and January 31, 2018. We summarize them according to these axes: types of analytics tasks, types of deep learning model architectures, special challenges arising from health data and tasks and their potential solutions, as well as evaluation strategies. Results: We surveyed and analyzed multiple aspects of the 98 articles we found and identified the following analytics tasks: disease detection/classification, sequential prediction of clinical events, concept embedding, data augmentation, and EHR data privacy. We then studied how deep architectures were applied to these tasks. We also discussed some special challenges arising from modeling EHR data and reviewed a few popular approaches. Finally, we summarized how performance evaluations were conducted for each task. Discussion: Despite the early success in using deep learning for health analytics applications, there still exist a number of issues to be addressed. We discuss them in detail including data and label availability, the interpretability and transparency of the model, and ease of deployment.

Indexed as

Deep LearningElectronic Health RecordsData AnonymizationDiseaseHumansNeural Networks, ComputerPrognosis

Identifiers

PMID29893864
PMCPMC6188527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.