Evidence map›Paper›PMID 29893821›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy.

Arthur W D Edridge, Martin Deijs, Ruth Namazzi, Cosimo Cristella, Maarten F Jebbink, Irma Maurer, Neeltje A Kootstra, Linda R Buluma, Job B M van Woensel, Menno D de Jong and 3 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  7. Gemykibivirus detection in acute encephalitis patients from Nepal.medRxiv : the preprint server for health sciences · 2024
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  19. Emerging orthobunyaviruses associated with CNS disease.PLoS neglected tropical diseases · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Arthur W D EdridgeLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Martin DeijsLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Ruth NamazziDepartment of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
Cosimo CristellaLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Maarten F JebbinkLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Irma MaurerLaboratory of Viral Immune Pathogenesis, Department of Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands.
Neeltje A KootstraLaboratory of Viral Immune Pathogenesis, Department of Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands.
Linda R BulumaDepartment of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
Job B M van WoenselGlobal Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
Menno D de JongLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Richard IdroDepartment of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
Michael Boele van HensbroekGlobal Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
Lia van der HoekLaboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
Academic Medical Center · NLMulago Hospital · UGMakerere University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its closest relative. The virus was named Ntwetwe virus, after the hometown of the patient.

Indexed as

Bunyaviridae InfectionsCerebrospinal FluidChild, PreschoolEncephalitis, ViralFemaleGenotypeHumansMetagenomicsOrthobunyavirusUganda

Identifiers

PMID29893821
PMCPMC6293039
OpenAlexW2807072214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.