Evidence map›Paper›PMID 29893042›Full record

ArticleJournal of diabetes2019

Prospective cohort studies of birth weight and risk of obesity, diabetes, and hypertension in adulthood among the Chinese population.

Qinghua Xia, Hui Cai, Yong-Bing Xiang, Peng Zhou, Honglan Li, Gong Yang, Yu Jiang, Xiao-Ou Shu, Wei Zheng, Wang-Hong Xu

Open access · hybridAbstract read
In one paragraph

Article in Journal of diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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  14. Schizophrenia Mortality: Barriers to Progress.The Psychiatric quarterly · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Qinghua XiaCenter for Disease Control and Prevention of Changning District, Shanghai, China.
Hui CaiDivision of Epidemiology, Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Yong-Bing XiangState Key Laboratory of Oncogene and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Peng ZhouCenter for Disease Control and Prevention of Changning District, Shanghai, China.
Honglan LiState Key Laboratory of Oncogene and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Gong YangDivision of Epidemiology, Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Yu JiangCenter for Disease Control and Prevention of Changning District, Shanghai, China.
Xiao-Ou ShuDivision of Epidemiology, Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Wei ZhengDivision of Epidemiology, Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Wang-Hong XuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-2045-2218
Vanderbilt University · USShanghai Municipal Center For Disease Control Prevention · CNRenji Hospital · CNFudan University · CN

Funding

Cohort Study of Cancer inhibitory Factors in MenR01CA082729 · NCI · VANDERBILT UNIVERSITY · PI SHU, XIAO-OU · 2001 to 2011
$6.3M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Shanghai Men's Health StudyUM1CA173640 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU · 2013 to 2017
$4.9M
Cancer Risk Reduction and Diet: A Cohort Study of WomenR37CA070867 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2009 to 2013
$4.7M
NCI NIH HHS R01 CA082729NCI NIH HHS R37 CA070867NCI NIH HHS UM1 CA173640NCI NIH HHS UM1 CA182910
6 · The paper itself

Abstract

backgroundLow birth weight (LBW) has been associated with subsequent risks of obesity and certain chronic diseases, but evidence for the associations is limited for the Chinese population.

methodsIn this study we analyzed data from two population-based prospective cohort studies, the Shanghai Women's Health Study and the Shanghai Men's Health Study, to examine the associations between LBW and the risk of obesity and chronic diseases. Birth weight was self-reported at baseline; anthropometric measurements were made at study enrollment. Type 2 diabetes mellitus (T2DM) diagnoses were self-reported, whereas hypertension diagnoses were based on self-report and blood pressure measurements at baseline and follow-up surveys.

resultsBirth weight was available for 11 515 men and 13 569 women. Non-linear associations were observed for birth weight with baseline body mass index (BMI), waist circumference (WC), waist:  hip ratio (WHR), and waist:  height ratio (WHtR; P < 0.05 for non-linearity), and LBW was linked with lower BMI, smaller WC, and larger WHR and WHtR. An excess risk of T2DM was observed for LBW (<2500 g) versus birth weight 2500-3499 g since baseline (hazard ratio [HR] 1.17; 95% confidence interval [CI] 0.92-1.49) and since birth (HR 1.29; 95% CI 1.07-1.54), whereas the HRs for hypertension since baseline and birth were 1.13 (95% CI 1.01-1.27) and 1.20 (95% CI 1.11-1.30), respectively. The risk of the diseases decreased as birth weight increased up to ~4000 g; further increases in birth weight did not convey additional benefits.

conclusionThe results suggest that LBW, an index of poor intrauterine nutrition, may affect health risks later in life in the Chinese population.

Indexed as

AdultAsian PeopleBirth WeightBlood PressureBody Weights and MeasuresChinaDiabetes Mellitus, Type 2FemaleHealth SurveysHumansHypertensionMaleMiddle AgedObesityProspective StudiesRisk Factors2型糖尿病birth weighthypertensionobesitytype 2 diabetes出生体重肥胖高血压

Identifiers

PMID29893042
PMCPMC6334524
OpenAlexW2808673677

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.