Evidence map›Paper›PMID 29892932›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2018

Higher frequency of upper gastrointestinal symptoms in healthy young Japanese females compared to males and older generations.

Kojiro Kawachi, Yasuhisa Sakata, Megumi Hara, Eri Takeshita, Hiroharu Kawakubo, Daisuke Yamaguchi, Norihiro Okamoto, Ryo Shimoda, Ryuichi Iwakiri, Nanae Tsuruoka and 2 more

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In one paragraph

Article in Esophagus : official journal of the Japan Esophageal Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kojiro KawachiDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Yasuhisa SakataDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Megumi HaraDepartments of Preventive Medicine, Saga Medical School, Saga, Japan.
Eri TakeshitaDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Hiroharu KawakuboDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Daisuke YamaguchiDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Norihiro OkamotoDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Ryo ShimodaDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Ryuichi IwakiriDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Nanae TsuruokaDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Motoyasu KusanoDepartment of Endoscopy and Endoscopic Surgery, Gunma University Hospital, Gunma, Japan.
Kazuma FujimotoDepartments of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan. fujimotk@cc.saga-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the differences in upper gastrointestinal symptoms between generations and genders in relatively healthy Japanese subjects.

methodsAltogether, 4086 healthy Japanese male and female (M/F) adults (M/F: 2244/1842) were analyzed. Among them, 3505 subjects (M/F: 1922/1583) were underwent a routine medical checkup at one of five hospitals in Saga, Japan from January 2013 to December 2013. The others were 581 (M/F: 322/259) healthy young volunteers at the Saga Medical School from April 2007 to March 2013. The participants were asked to complete the frequency scale for the symptoms of gastroesophageal reflex disease (FSSG) questionnaire, undergo upper gastrointestinal endoscopy, and submit to a rapid urease test to diagnose Helicobacter pylori infection. Among the 4086 subjects, the 2414 who had no H. pylori infection and no positive endoscopic findings were enrolled in the study.

resultsSubjects' average age was 46.9 ± 12.2 years, with males' and females' ages being almost equivalent. The total FSSG score were high in females compared to males (P < 0.01) and decreased significantly with aging (P < 0.05). Among the generations, FSSG scores were the highest for those 20-29 years old, and they were significantly decreased with ageing in both males and females (P < 0.05).

conclusionThe FSSG score was significantly higher in healthy Japanese females than in males, and the scores decreased with aging.

Indexed as

Helicobacter pyloriSymptom AssessmentAdultAgedAge FactorsBreath TestsEndoscopy, GastrointestinalFemaleGastroesophageal RefluxHealthy VolunteersHelicobacter InfectionsHumansJapanMaleMiddle AgedSex FactorsUreaseAcid-related dyspepsiaFrequency scale for the symptoms of GERDGastroesophageal reflux diseaseReflux symptoms

Identifiers

PMID29892932
PMCPMC5884897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.