Evidence map›Paper›PMID 29892930›Full record

ReviewEsophagus : official journal of the Japan Esophageal Society2018

Angiogenic factors: role in esophageal cancer, a brief review.

Kátia Ladeira, Filipa Macedo, Adhemar Longatto-Filho, Sandra F Martins

Abstract readReview
PubMed Publisher
In one paragraph

Review in Esophagus : official journal of the Japan Esophageal Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Targeting the Microenvironment in Esophageal Cancer.Frontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Factors Associated With Esophagus Cancers in Togo, Sub-Saharan Africa.Clinical pathology (Thousand Oaks, Ventura County, Calif.)
    Article
  15. Cytokine Interaction With Cancer-Associated Fibroblasts in Esophageal Cancer.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kátia LadeiraPortuguese Oncology Institute, Lisbon, Portugal.
Filipa MacedoPortuguese Oncology Institute, Coimbra, Portugal.
Adhemar Longatto-FilhoLife and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Sandra F MartinsLife and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal. sandramartins@med.uminho.pt.ORCID 0000-0002-3526-3199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer has an aggressive behavior with rapid tumor mass growth and frequently poor prognosis; it is known as one of the most fatal types of cancer worldwide. The identification of potential molecular markers that can predict the response to treatment and the prognosis of this cancer has been subject of a vast investigation in the recent years. Among several molecules, various angiogenic factors that are linked to the tumor development, growth, and invasion, such as VEGF, HGF, angiopoietin-2, IL-6, and TGF-B1, were investigated. In this paper, the authors sought to review the role of these angiogenic factors in prognosis and hypothesize how they can be used as a treatment target.

Indexed as

Neovascularization, PathologicAngiopoietin-2Biomarkers, TumorEsophageal NeoplasmsFibroblast Growth FactorsFollistatinHepatocyte Growth FactorHumansHypoxia-Inducible Factor 1, alpha SubunitInterleukin-6PrognosisTransforming Growth Factor beta1Vascular Endothelial Growth FactorsAngiopoietin-2ANGPT2 protein, humanBiomarkers, TumorFibroblast Growth FactorsFollistatinHepatocyte Growth FactorHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitIL6 protein, humanInterleukin-6Transforming Growth Factor beta1Vascular Endothelial Growth FactorsAngiopoietin-2Esophageal cancerHGFIL-6TGF-B1VEGF

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.