Evidence map›Paper›PMID 29892707›Full record

ArticleInternational journal of cardiology. Heart & vasculature2018

Improvement in the electrocardiograms associated with right ventricular hypertrophy after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension.

Takahiko Nishiyama, Seiji Takatsuki, Takashi Kawakami, Yoshinori Katsumata, Takehiro Kimura, Masaharu Kataoka, Hikaru Tsuruta, Yuji Itabashi, Mitsushige Murata, Shinsuke Yuasa and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  11. Assessment of electrocardiographic markers of acute and long-term hemodynamic improvement in patients with pulmonary hypertension.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Takahiko NishiyamaDepartment of Cardiology, Keio University School of Medicine, Japan.
Seiji TakatsukiDepartment of Cardiology, Keio University School of Medicine, Japan.
Takashi KawakamiDepartment of Cardiology, Keio University School of Medicine, Japan.
Yoshinori KatsumataDepartment of Cardiology, Keio University School of Medicine, Japan.
Takehiro KimuraDepartment of Cardiology, Keio University School of Medicine, Japan.
Masaharu KataokaDepartment of Cardiology, Keio University School of Medicine, Japan.
Hikaru TsurutaDepartment of Cardiology, Keio University School of Medicine, Japan.
Yuji ItabashiDepartment of Cardiology, Keio University School of Medicine, Japan.
Mitsushige MurataDepartment of Cardiology, Keio University School of Medicine, Japan.
Shinsuke YuasaDepartment of Cardiology, Keio University School of Medicine, Japan.
Yoshiyasu AizawaDepartment of Cardiology, Keio University School of Medicine, Japan.
Keiichi FukudaDepartment of Cardiology, Keio University School of Medicine, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBalloon pulmonary angioplasty (BPA) is a treatment option for patients with chronic thromboembolic pulmonary hypertension (CTEPH). METHODS AND

resultsIn 60 patients with CTEPH, we examined the hemodynamic data before and after BPA. In addition, the sequential ECG findings for right ventricular hypertrophy (RVH) were assessed. The mean pulmonary arterial pressure (mPAP) decreased from 38 ± 11 to 20 ± 4 mm Hg (p < 0.05). The ROC analysis showed that the S waves in V5, R waves in V1 + S waves in V5, S waves in I, and QRS axis were significant predictors of an mPAP ≧ 30 mm Hg (AUC > 0.75, p < 0.01). The predictive values for the mPAP before the BPA were the S and R waves in lead V6, and P waves in lead II (33.417 + 0.078 × P in II - 0.10 × R in V6 + 0.012 × S in V6). The change in the mPAP (ΔmPAP) correlated with the change in the amplitudes of the ECGs: ΔS wave in lead I (R = 0.544, p < 0.001), ΔR in V1 + S in V5 (R = 0.476, p < 0.001), and ΔP wave in II (R = 0.511, p < 0.001). At 6 months of follow-up, the improvement in an R in V1 + S in V5 of ≧10 mm implied a better functional status.

conclusionBPA therapy reduced the pulmonary arterial pressure in patients with CTEPH and was associated with an improvement in the ECG findings related to RVH.

Indexed as

Balloon pulmonary angioplastyChronic thromboembolic pulmonary hypertensionElectrocardiogramRight ventricular hypertrophy

Identifiers

PMID29892707
PMCPMC5993172
OpenAlexW2804894488

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.