Evidence map›Paper›PMID 29892559›Full record

ArticleBiochimie open2018

Lack of current observed in HEK293 cells expressing NALCN channels.

Jennifer M Egan, Colleen A Peterson, W Mark Fry

Open access · hybridAbstract read
In one paragraph

Article in Biochimie open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer M EganDepartment of Biological Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.
Colleen A PetersonDepartment of Biological Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.
W Mark FryDepartment of Biological Sciences, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sodium leak channel NALCN is poorly understood, but is reported as a Na

Indexed as

ERS, external recording solutionHEK293IRS, internal recording solutionM3R, M3 muscarinic receptorMuscarinic receptorNALCNNALCN, sodium leak channel, non-selectivePatch clamp

Identifiers

PMID29892559
PMCPMC5991895
OpenAlexW2789771440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.