Evidence map›Paper›PMID 29892549›Full record

ArticleLeukemia research reports2018

A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia.

Mattias Hofmans, Anke Delie, Karl Vandepoele, Nadine Van Roy, Joni Van der Meulen, Jan Philippé, Ine Moors

Open access · goldAbstract readCase Reports
In one paragraph

Article in Leukemia research reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Acute Myeloid Leukemia WithCase reports in hematology · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mattias HofmansDepartment of Clinical Chemistry, Microbiology and Immunology, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Anke DelieDepartment of Hematology, Ghent University Hospital, Ghent, Belgium.
Karl VandepoeleLaboratory for Molecular Hematology, Ghent University Hospital, Ghent, Belgium.
Nadine Van RoyDepartment of Medical Genetics, Ghent University Hospital, Ghent, Belgium.
Joni Van der MeulenDepartment of Medical Genetics, Ghent University Hospital, Ghent, Belgium.
Jan PhilippéDepartment of Clinical Chemistry, Microbiology and Immunology, Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Ine MoorsDepartment of Hematology, Ghent University Hospital, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural history of primary eosinophilia remains highly variable and is characterized by underlying disease heterogeneity. Chronic eosinophilic leukemia, not otherwise specified (CEL-NOS) is a rare and aggressive disease characterized by non-specific cytogenetic abnormalities or elevated blasts, with high risk of transformation to acute leukemia. We describe a case of CEL-NOS with two hierarchically related non-specific cytogenetic rearrangements, associated with an

Indexed as

CEL-NOSDecitabineHypereosinophiliaNPM1 mutationSecondary AML

Identifiers

PMID29892549
PMCPMC5993353
OpenAlexW2797895473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.