ArticleTranslational vision science & technology2018
A Method Using Goldmann Stimulus Sizes I to V-Measured Sensitivities to Predict Lead Time Gained to Visual Field Defect Detection in Early Glaucoma.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Multiple attention based deep multimodal fusion network for glaucoma and neurodegenerative disease diagnosis.Scientific reports · 2026Article
- Predicting Variability and Reliability in Visual Field Testing: Short- and Long-Term Approaches.Ophthalmology science · 2026Article
- Visual Function Loss Through Opacified Media: Comparison Between Single- and Two-Photon Vision.Translational vision science & technology · 2026Article
- Perimetric Stimuli Undergoing Complete Spatial Summation Optimize the Detection of Retinal Ganglion Cell Density Gradients in Healthy Observers.Translational vision science & technology · 2025Article
- The effects of transitioning from SITA-Standard to SITA-Fast or SITA-Faster on sensitivities below the measurement floor.AJO international · 2025Article
- Retinal Ganglion Cell Content Underlying Standard Automated Perimetry Size I to V Visual Sensitivities in the Non-Human Primate Experimental Glaucoma Model.Investigative ophthalmology & visual science · 2024Article
- Prediction of visual field defects from macular optical coherence tomography in glaucoma using cluster analysis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022Article
- Custom extraction of macular ganglion cell-inner plexiform layer thickness more precisely co-localizes structural measurements with visual fields test grids.Scientific reports · 2020Article
- Development of a Spatial Model of Age-Related Change in the Macular Ganglion Cell Layer to Predict Function From Structural Changes.American journal of ophthalmology · 2019Article
- An evidence-based approach to the routine use of optical coherence tomography.Clinical & experimental optometry · 2019Review
- Comparison of defect depths for sinusoidal and circular perimetric stimuli in patients with glaucoma.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2019Article
- Optimising the Structure-Function Relationship at the Locus of Deficit in Retinal Disease.Frontiers in neuroscience · 2019Article
- Neutralizing Peripheral Refraction Eliminates Refractive Scotomata in Tilted Disc Syndrome.Optometry and vision science : official publication of the American Academy of Optometry · 2018Article
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4 authors.
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Abstract
purposeTo predict the lead time (difference in time taken for a visual field [VF] defect to be detected) obtained when using stimulus sizes within or near the size of the critical area of spatial summation (Ac), and to test these predictions using sensitivity measurements from a cohort of glaucoma patients.
methodsThirty-seven patients with early open-angle glaucoma and 60 healthy observers underwent VF testing on the Humphrey Field Analyzer in full threshold mode using Goldmann stimulus sizes I to V (GI-V) across the 30-2 test grid. We used the sensitivities measured using GI to V in healthy patients to predict the lead time gained by using stimulus sizes within the size of Ac at all locations within the 30-2 grid. Then, we used sensitivities measured in the glaucoma patients to test this predictive model.
resultsMedian lead time to VF defect detection when using stimulus sizes within Ac compared with stimulus sizes larger than Ac was 4.1 years across the 30-2 test grid (interquartile range, 3.1 and 5.1 years). Sensitivities of the glaucoma patients showed good agreement with the predictive model of lead time gained (77.5%-84.3% were within ±3 dB).
conclusionsOur model predicted substantial lead time differences when using stimulus sizes within or near Ac. Such stimulus sizes could potentially detect VF defects, on average, 4 years earlier than current paradigms. TRANSLATIONAL RELEVANCE: Stimulus sizes within or near Ac may be more suitable for early detection of glaucomatous VF defects. Larger stimulus sizes may be more suitable for later monitoring of established disease.
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