Evidence map›Paper›PMID 29892262›Full record

ArticleFrontiers in endocrinology2018

Stephanie Post, Galina Karashchuk, John D Wade, Waseem Sajid, Pierre De Meyts, Marc Tatar

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
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  3. Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
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  7. The insulin-like peptides Dilp2 and Dilp6 exhibit divergent responses to dietary sugar and protein inProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Stephanie PostDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, United States.
Galina KarashchukDepartment of Ecology and Evolutionary Biology, Brown University, Providence, RI, United States.
John D WadeFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Waseem SajidLEO Pharma A/S, Ballerup, Denmark.
Pierre De MeytsDepartment of Cell Signalling, de Duve Institute, Brussels, Belgium.
Marc TatarDepartment of Ecology and Evolutionary Biology, Brown University, Providence, RI, United States.
Brown University · USFlorey Institute of Neuroscience and Mental Health · AULeo Pharma (Denmark) · DKNovo Nordisk (Denmark) · DK

Funding

FUNCTIONS AND INTERACTIONS DFOXO IN DROSOPHILA AGINGR37AG024360 · NIA · BROWN UNIVERSITY · PI TATAR, MARC · 2011 to 2020
$4.5M
Predoctoral Training in the Molecular Biology of AgingT32AG041688 · NIA · BROWN UNIVERSITY · PI NICOLA NERETTI, John M Sedivy · 2012 to 2026
$3.5M
NIA NIH HHS R37 AG024360NIA NIH HHS T32 AG041688
6 · The paper itself

Abstract

Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including growth, development, metabolism, stress responses, and aging.

Indexed as

agingDrosophila insulin-like peptidesglycogenglycogen phosphorylaseIGFinsulinmetabolismsignaling bias

Identifiers

PMID29892262
PMCPMC5985746
OpenAlexW2799840159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.