Evidence map›Paper›PMID 29892076›Full record

ArticleScientific reports2018

Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine.

Sven Johannsson, Piotr Neumann, Alexander Wulf, Luisa M Welp, Hans-Dieter Gerber, Matthias Krull, Ulf Diederichsen, Henning Urlaub, Ralf Ficner

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sven JohannssonDepartment of Molecular Structural Biology, Institute of Microbiology and Genetics, GZMB, Georg-August-University Göttingen, 37077, Göttingen, Germany.
Piotr NeumannDepartment of Molecular Structural Biology, Institute of Microbiology and Genetics, GZMB, Georg-August-University Göttingen, 37077, Göttingen, Germany.
Alexander WulfBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Biophysical Chemistry, Am Faßberg 11, 37077, Göttingen, Germany.
Luisa M WelpBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Biophysical Chemistry, Am Faßberg 11, 37077, Göttingen, Germany.
Hans-Dieter GerberInstitut für Pharmazeutische Chemie der Philipps-Universität Marburg, Marbacher Weg 6, 35032, Marburg, Germany.
Matthias KrullInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany.
Ulf DiederichsenInstitut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany.
Henning UrlaubBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Biophysical Chemistry, Am Faßberg 11, 37077, Göttingen, Germany.
Ralf FicnerDepartment of Molecular Structural Biology, Institute of Microbiology and Genetics, GZMB, Georg-August-University Göttingen, 37077, Göttingen, Germany. rficner@uni-goettingen.de.ORCID 0000-0002-1739-6086
University of Göttingen · DEMax Planck Institute for Biophysical Chemistry · DEPhilipps University of Marburg · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dnmt2 methylates cytosine at position 38 of tRNA

Indexed as

Catalytic DomainCrystallography, X-RayDNA (Cytosine-5-)-MethyltransferasesEnzyme ActivatorsMass SpectrometryModels, MolecularMolecular Docking SimulationNucleoside QProtein BindingProtein ConformationRNA, Transfer, AspSchizosaccharomycesDNA (Cytosine-5-)-MethyltransferasesEnzyme ActivatorsNucleoside QRNA, Transfer, Asp

Identifiers

PMID29892076
PMCPMC5995894
OpenAlexW2805172502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.