Evidence map›Paper›PMID 29892015›Full record

SynthesisNature genetics2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Carolina Roselli, Mark D Chaffin, Lu-Chen Weng, Stefanie Aeschbacher, Gustav Ahlberg, Christine M Albert, Peter Almgren, Alvaro Alonso, Christopher D Anderson, Krishna G Aragam and 208 more

2 registry-linked trialsOpen access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Nature genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 496 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
496citing papers in PubMed, 16 pooled it
60.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04331535 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care

TypeinterventionalSponsorBoston VA Research Institute, Inc.Ran2020 to 2025Enrolled1,076ConditionsCoronary Artery Disease, Atrial Fibrillation, Type 2 Diabetes, Colorectal CancerArmsPolygenic risk score (PRS)
NCT07641582 narecruitingnot on this mapstarted 2024, after this paper: background citation

Development of an Atrial Fibrillation Prediction Model Using Polygenic Risk Score: A Prospective Cohort Study

TypeinterventionalSponsorSeoul St. Mary's HospitalRan2024 to 2027Enrolled800ConditionsAtrial Fibrillation (AF)Arms7-day continuous ECG patch monitor, Six-lead handheld electrocardiogram device, SNP array genotyping
3 · Its place in the literature

Who cites it

496 citing papers in PubMed, 16 syntheses or guidelines pooled it, 791 citations in OpenAlex.

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436 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

218 authors at 20 institutions in 20 countries.

Carolina RoselliProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-5267-6756
Mark D ChaffinProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-1234-5562
Lu-Chen WengProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Stefanie AeschbacherUniversity Hospital Basel, Basel, Switzerland.
Gustav AhlbergLaboratory for Molecular Cardiology, The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Christine M AlbertDivisions of Preventive and Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA, USA.
Peter AlmgrenDepartment of Clinical Sciences, Lund University, Malmo, Sweden.ORCID http://orcid.org/0000-0002-0473-0241
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-2225-8323
Christopher D AndersonProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Krishna G AragamProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Dan E ArkingMcKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John BarnardDepartments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0003-2403-8268
Traci M BartzCardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA.
Emelia J BenjaminNHLBI and Boston University's Framingham Heart Study, Framingham, MA, USA.ORCID http://orcid.org/0000-0003-4076-2336
Nathan A BihlmeyerPredoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Joshua C BisCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Heather L BloomDivision of Cardiology, Emory University and Atlanta VA Medical Center, Atlanta, GA, USA.
Eric BoerwinkleHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Erwin B BottingerThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jennifer A BrodyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8509-148X
Hugh CalkinsJohns Hopkins University, Baltimore, MD, USA.
Archie CampbellGeneration Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-0198-5078
Thomas P CappolaPenn Cardiovascular Institute and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
John CarlquistIntermountain Heart Institute, Intermountain Medical Center, Murray, UT, USA.
Daniel I ChasmanProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Lin Y ChenCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Yii-Der Ida ChenInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Eue-Keun ChoiSeoul National University Hospital, Seoul, Korea.
Seung Hoan ChoiProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Ingrid E ChristophersenProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6141-4712
Mina K ChungDepartments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
John W ColeBaltimore Veterans Affairs Medical Center, Department of Neurology, Baltimore, MD, USA.
David ConenUniversity Hospital Basel, Basel, Switzerland.
James CookDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
Harry J CrijnsMaastricht University Medical Center+ and Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands.
Michael J CutlerIntermountain Heart Institute, Intermountain Medical Center, Murray, UT, USA.
Scott M DamrauerDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Brian R DanielsProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Dawood DarbarUniversity of Illinois Chicago, Chicago, IL, USA.
Graciela DelgadoVth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Joshua C DennyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Martin DichgansInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-0654-387X
Marcus DörrDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Elton A DudinkMaastricht University Medical Center+ and Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-4572-3969
Samuel C DudleyCardiovascular Division and Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, USA.
Nada EsaUniversity of Massachusetts Medical School Worcester, Worcester, MA, USA.
Tonu EskoProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-1982-6569
Markku EskolaHeart Center, Department of Cardiology, Tampere University Hospital, Finland and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Diane FatkinVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Stephan B FelixDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Ian FordRobertson Center for Biostatistics, University of Glasgow, Glasgow, UK.
Oscar H FrancoDepartment of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Bastiaan GeelhoedDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Raji P GrewalDept. of Neuroscience, Saint Francis Medical Center, Trenton, NJ, USA.
Vilmundur GudnasonIcelandic Heart Association, Kopavogur, Iceland.
Xiuqing GuoInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Namrata GuptaProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Stefan GustafssonDepartment of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5894-0351
Rebecca GutmannDivision of Cardiovascular Medicine and Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, USA.
Anders HamstenCardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Tamara B HarrisLaboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA.
Caroline HaywardMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-9405-9550
Susan R HeckbertCardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA.
Jussi HernesniemiHeart Center, Department of Cardiology, Tampere University Hospital, Finland and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Lynne J HockingInstitute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
Albert HofmanDepartment of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Andrea R V R HorimotoLaboratory of Genetics and Molecular Cardiology, Heart Institute, University of São Paulo, São Paulo, Brazil.
Jie HuangBoston VA Research Institute, Inc., Boston, MA, USA.
Paul L HuangCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Jennifer HuffmanMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-9672-2491
Erik IngelssonDepartment of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Esra Gucuk IpekJohns Hopkins University, Baltimore, MD, USA.
Kaoru ItoLaboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Jordi Jimenez-CondeDepartment of Neurology, Neurovascular Research Group IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions Médiques), Barcelona, Spain.
Renee JohnsonVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-3246-8359
Stefan KääbDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Yoichiro KamataniLaboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0001-8748-5597
John P KaneCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.
Adnan KastratiDZHK (German Centre for Cardiovascular Research), partner site: Munich Heart Alliance, Munich, Germany.
Sekar KathiresanProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6724-032X
Petra Katschnig-WinterDepartment of Neurology, Medical University of Graz, Graz, Austria.
Maryam KavousiDepartment of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Thorsten KesslerDeutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, Germany.
Bas L KietselaerMaastricht University Medical Center+ and Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands.
Paulus KirchhofInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.
Marcus E KleberVth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0663-7275
Stacey KnightIntermountain Heart Institute, Intermountain Medical Center, Murray, UT, USA.
Jose E KriegerLaboratory of Genetics and Molecular Cardiology, Heart Institute, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5464-1792
Michiaki KuboRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Lenore J LaunerLaboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA.
Jari LaurikkaDepartment of Cardio-Thoracic Surgery, Heart Center, Tampere University Hospital, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Kirsten LeineweberDept. Disease Genomics, Bayer, Wuppertal, Germany.
Rozenn N LemaitreCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Man LiDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-3839-0281
Hong Euy LimKorea University Guro Hospital, Seoul, Korea.
Henry J LinInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Honghuang LinNHLBI and Boston University's Framingham Heart Study, Framingham, MA, USA.ORCID http://orcid.org/0000-0003-3043-3942
Lars LindDepartment of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
Cecilia M LindgrenWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Marja-Liisa LokkiTransplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland.
Barry LondonDivision of Cardiovascular Medicine and Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, USA.
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-8532-5087
Siew-Kee LowLaboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Yingchang LuThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Leo-Pekka LyytikäinenDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.ORCID http://orcid.org/0000-0002-7200-5455
Peter W MacfarlaneInstitute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Patrik K MagnussonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-7315-7899
Anubha MahajanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-5585-3420
Rainer MalikInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Alfredo J MansurHeart Institute, University of São Paulo, São Paulo, Brazil.
Gregory M MarcusDivision of Cardiology, University of California, San Francisco, San Francisco, California, USA.
Lauren MargolinProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Kenneth B MarguliesPenn Cardiovascular Institute and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Winfried MärzClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
David D McManusUniversity of Massachusetts Medical School Worcester, Worcester, MA, USA.
Olle MelanderDepartment of Internal Medicine, Clinical Sciences, Lund University, Malmo, Sweden.
Sanghamitra MohantyTexas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, TX, USA.
Jay A MontgomeryDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael P MorleyPenn Cardiovascular Institute and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Andrew P MorrisDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
Martina Müller-NurasyidDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany.ORCID http://orcid.org/0000-0003-3793-5910
Andrea NataleTexas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, TX, USA.
Saman NazarianUniversity of Pennsylvania, Philadelphia, PA, USA.
Benjamin NeumannDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany.
Christopher Newton-ChehProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Maartje N NiemeijerDepartment of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kjell NikusHeart Center, Department of Cardiology, Tampere University Hospital, Finland and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Peter NilssonDepartment of Clinical Sciences, Lund University and Skåne University Hospital, Malmo, Sweden.
Raymond NoordamSection of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Heidi OellersAtrial Fibrillation NETwork, Muenster, Germany.
Morten S OlesenLaboratory for Molecular Cardiology, The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Marju Orho-MelanderDepartment of Clinical Sciences, Lund University, Malmo, Sweden.
Sandosh PadmanabhanInstitute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Hui-Nam PakYonsei University Health System, Seoul, Korea.
Guillaume ParéPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Nancy L PedersenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Joanna PeraDepartment of Neurology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Alexandre PereiraLaboratory of Genetics and Molecular Biology, Heart Institute, University of São Paulo, São Paulo, Brazil.
David PorteousGeneration Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Bruce M PsatyKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Sara L PulitProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-2502-3669
Clive R PullingerCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.
Daniel J RaderDivision of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Lena RefsgaardLaboratory for Molecular Cardiology, The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Marta RibasésPsychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-1039-1116
Paul M RidkerDivisions of Preventive and Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA, USA.
Michiel RienstraDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-2581-070X
Lorenz RischUniversity Institute of Clinical Chemistry, University of Bern, Bern, Switzerland.
Dan M RodenDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jonathan RosandProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Michael A RosenbergCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Natalia RostProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jerome I RotterInstitute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Samir SabaDivision of Cardiology, University of Pittsburgh, Pittsburgh, PA, USA.
Roopinder K SandhuDivision of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Renate B SchnabelDepartment of General and Interventional Cardiology, University Heart Centre Hamburg, Hamburg, Germany.
Katharina SchrammDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany.
Heribert SchunkertDZHK (German Centre for Cardiovascular Research), partner site: Munich Heart Alliance, Munich, Germany.
Claudia SchurmanThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stuart A ScottDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-5720-1864
Ilkka SeppäläDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.ORCID http://orcid.org/0000-0002-5595-2573
Christian ShafferDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Svati ShahDivision of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Alaa A ShalabyDivision of Cardiology, University of Pittsburgh, Pittsburgh, PA, USA.
Jaemin ShimKorea University Anam Hospital, Seoul, Korea.
M Benjamin ShoemakerDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Joylene E SilandDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0003-4404-1245
Juha SinisaloHeart and Lung Center HUS, Helsinki University Central Hospital, Helsinki, Finland.ORCID http://orcid.org/0000-0002-0169-5137
Moritz F SinnerDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany.
Agnieszka SlowikDepartment of Neurology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Albert V SmithIcelandic Heart Association, Kopavogur, Iceland.ORCID http://orcid.org/0000-0003-1942-5845
Blair H SmithDivision of Population Health Sciences, University of Dundee, Dundee, UK.ORCID http://orcid.org/0000-0002-5362-9430
J Gustav SmithProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jonathan D SmithDepartments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-0415-386X
Nicholas L SmithCardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA.
Elsayed Z SolimanEpidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston Salem, NC, USA.ORCID http://orcid.org/0000-0001-5632-8150
Nona SotoodehniaCardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA.
Bruno H StrickerDepartment of Epidemiology and Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Albert SunDivision of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Han SunDepartments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
Jesper H SvendsenLaboratory for Molecular Cardiology, The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8466-8515
Toshihiro TanakaDepartment of Human Genetics and Disease Diversity, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6201-9784
Kahraman TanriverdiUniversity of Massachusetts Medical School Worcester, Worcester, MA, USA.
Kent D TaylorInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Maris Teder-LavingEstonian Genome Center, University of Tartu, Tartu, Estonia.
Alexander TeumerDZHK (German Centre for Cardiovascular Research), partner site: Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-8309-094X
Sébastien ThériaultPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Stella TrompetDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Nathan R TuckerProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-5071-4218
Arnljot TveitDepartment of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Andre G UitterlindenDepartment of Epidemiology and Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Pim Van Der HarstDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-2713-686X
Isabelle C Van GelderDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
David R Van WagonerDepartments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-8250-9828
Niek VerweijDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-4303-7685
Efthymia VlachopoulouTransplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland.
Uwe VölkerDZHK (German Centre for Cardiovascular Research), partner site: Greifswald, Greifswald, Germany.
Biqi WangDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Peter E WeekeLaboratory for Molecular Cardiology, The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Bob WeijsMaastricht University Medical Center+ and Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-3202-4931
Raul WeissDivision of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA.
Stefan WeissDZHK (German Centre for Cardiovascular Research), partner site: Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-3553-4315
Quinn S WellsDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kerri L WigginsCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2749-1279
Jorge A WongDivision of Cardiology, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Daniel WooUniversity of Cincinnati College of Medicine, Cincinnati, OH, USA.
Bradford B WorrallDepartments of Neurology and Public Health Science, University of Virginia Health System, Charlottesville, VA, USA.
Pil-Sung YangYonsei University Health System, Seoul, Korea.
Jie YaoInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Zachary T YonedaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Tanja ZellerDepartment of General and Interventional Cardiology, University Heart Centre Hamburg, Hamburg, Germany.
Lingyao ZengDeutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, Germany.
Steven A LubitzProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-9599-4866
Kathryn L LunettaNHLBI and Boston University's Framingham Heart Study, Framingham, MA, USA.
Patrick T EllinorProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA. ellinor@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-2067-0533
Broad Institute · USVanderbilt University Medical Center · USTampere University · FIUniversity Medical Center Groningen · NLUniversity of Washington · USBoston University · USErasmus MC · NLThe Lundquist Institute · USUniversity of Pennsylvania · USCleveland Clinic · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USLund University · SEMaastricht University · NLMünchen Klinik · DERIKEN Center for Integrative Medical Sciences · JPUniversity of Copenhagen · DKBrigham and Women's Hospital · USKaiser Permanente Washington Health Research Institute · USKarolinska Institutet · SE

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
CLINICAL PHARMACOLOGY TRAINING PROGRAMT32GM007569 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Bjorn C Knollmann · 1985 to 2026
$12.4M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Rare variants and NHLBI traits in deeply phenotyped cohortsR01HL120393 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, RICE, KENNETH M. · 2014 to 2016
$8.9M
CHS research resources for the cardiovascular health of older adultsU01HL130114 · NHLBI · UNIVERSITY OF WASHINGTON · PI BURKE, GREGORY L, KRONMAL, RICHARD A · 2016 to 2019
$6.6M
CLINICAL PROJECT: Age, Gene/Environment Susceptibility Study on the Multi-omics of Aging: A clinical epidemiologic prospective studyZIAAG007380 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2009 to 2025
$6.1M
Functional Genomics of Atrial Fibrillation in Human AtriaR01HL111314 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2012 to 2019
$6.1M
Rare variants and NHLBI traits in deeply phenotyped cohortsU01HL120393 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, RICE, KENNETH M. · 2017 to 2018
$5.6M
Diverse ancestry biobank to map biomedical traits and elucidate health disparitieU01HG007417 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LOOS, RUTH JF · 2013 to 2017
$3.5M
Genomics of Cardiac ArrhythmiasR01HL139731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2018 to 2022
$3.3M
AFGen Consortium: Atrial Fibrillation Genomics to Functional AnalysesR01HL128914 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2015 to 2018
$3.1M
Genetics of Atrial FibrillationR01HL090620 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2008 to 2012
$2.9M
American Heart Association-American Stroke Association 16EIA26410001Doris Duke Charitable Foundation 2014105Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NHGRI NIH HHS U01 HG007417NHLBI NIH HHS K23 HL127296NHLBI NIH HHS K24 HL105780NHLBI NIH HHS L30 HL123413NHLBI NIH HHS R01 HL090620NHLBI NIH HHS R01 HL092217NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL111314NHLBI NIH HHS R01 HL116747NHLBI NIH HHS R01 HL120393NHLBI NIH HHS R01 HL128914NHLBI NIH HHS R01 HL138737NHLBI NIH HHS R01 HL139731NHLBI NIH HHS U01 HL120393NHLBI NIH HHS U01 HL130114NIGMS NIH HHS T32 GM007569
6 · The paper itself

Abstract

Atrial fibrillation (AF) affects more than 33 million individuals worldwide

Indexed as

Atrial FibrillationCase-Control StudiesEthnicityGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansQuantitative Trait LociTranscriptome

Identifiers

PMID29892015
PMCPMC6136836
OpenAlexW2807295499

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.