Evidence map›Paper›PMID 29892000›Full record

ArticleScientific reports2018

The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.

Muhammad Fariz Zahir Ali, Indri Afriani Yasin, Takashi Ohta, Atsushi Hashizume, Atsushi Ido, Takayuki Takahashi, Chiemi Miura, Takeshi Miura

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Inhibition of pathogenic3 Biotech · 2020
    Article
  8. Article
  9. Replacing Fish Meal with Defatted Insect Meal (Yellow MealwormAnimals : an open access journal from MDPI · 2019
    Article
  10. Replacement of Fish Meal by Defatted Yellow Mealworm (Animals : an open access journal from MDPI · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad Fariz Zahir AliGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan.
Indri Afriani YasinGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan.
Takashi OhtaSouth Ehime Fisheries Research Center, Ehime University, 1289-1, Funakoshi, Ainan, Ehime, 798-4292, Japan.
Atsushi HashizumeGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan.
Atsushi IdoSouth Ehime Fisheries Research Center, Ehime University, 1289-1, Funakoshi, Ainan, Ehime, 798-4292, Japan.
Takayuki TakahashiGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan.
Chiemi MiuraGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan.
Takeshi MiuraGraduate School of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama, Ehime, 790-8566, Japan. miura.takeshi.mx@ehime-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously identified novel bioactive polysaccharides from Bactrocera cucurbitae and Antheraea yamamai that activate innate immunity in RAW264 murine macrophages. However, in terms of potential applications in the cultivation of prawns, there were problems with the availability of these insects. However, we have now identified a polysaccharide from Bombyx mori that activates innate immunity in RAW264 cells and penaeid prawns. This purified polysaccharide, termed silkrose of B. mori (silkrose-BM), has a molecular weight of 1,150,000 and produces a single symmetrical peak on HPLC. Eight of nine constitutive monosaccharides of silkrose-BM are concomitant with dipterose of B. cucurbitae (dipterose-BC) and silkrose of A. yamamai (silkrose-AY). The major differences are found in the molar ratios of the monosaccharides. Silkrose-BM is approximately 500-fold less potent than silkrose-AY (EC

Indexed as

AnimalsAquacultureBombyxChromatography, High Pressure LiquidImmunity, InnateImmunologic FactorsMacrophagesMiceMolecular WeightNitric OxidePenaeidaePolysaccharidesRAW 264.7 CellsSurvival AnalysisVibrio InfectionsImmunologic FactorsNitric OxidePolysaccharides

Identifiers

PMID29892000
PMCPMC5995915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.