Evidence map›Paper›PMID 29891805›Full record

ArticleNutrients2018

Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice.

Yutaka Matsunaga, Yasuyuki Sakata, Takumi Yago, Hirohiko Nakamura, Takashi Shimizu, Yasuhiro Takeda

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yutaka MatsunagaWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. yu-matsunaga@morinagamilk.co.jp.
Yasuyuki SakataWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. ys-sakata@morinagamilk.co.jp.
Takumi YagoWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. takumi-yago131@morinagamilk.co.jp.
Hirohiko NakamuraWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. hi_nakam@morinagamilk.co.jp.
Takashi ShimizuWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. t_simizu@morinagamilk.co.jp.
Yasuhiro TakedaWellness & Nutrition Science Institute, Morinaga Milk Industry Co., Ltd., 1-83-5 Higashihara, Zama-City 252-8583, Kanagawa Prefecture, Japan. ya_taked@morinagamilk.co.jp.
Megmilk Snow Brand (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have reported that post-exercise ingestion of carbohydrates with protein supplementation can enhance glycogen recovery. However, few reports have focused on the degrees of degradation of the ingested proteins due to post-exercise glycogen resynthesis. Accordingly, the aim of this study was to clarify the effects of differences in protein degradation on muscle glycogen recovery. Male seven-week-old C57BL/6J mice performed a single bout of 60-min treadmill running exercise and were then orally administered glucose (Glu; 1.5 mg/g body weight (BW)), glucose with casein peptide (Glu + Pep; 1.5 + 0.5 mg/g BW) or its constituent amino acid mixture (Glu + AA; 1.5 + 0.5 mg/g BW). At 120 min after supplementation, the soleus muscle glycogen content in the Glu and Glu + AA groups was significantly higher than that immediately after exercise; however, no such difference was observed in the Glu + Pep group. Blood substrate concentration and insulin signaling did not differ among the three groups. Furthermore, energy expenditure during the recovery period in the Glu + Pep group was significantly higher than that in the Glu and Glu + AA groups. These findings suggest that post-exercise co-ingestion of glucose and casein peptide might delay glycogen resynthesis, at least in part through increased energy expenditure caused by casein peptide ingestion.

Indexed as

Dietary SupplementsMuscle ContractionPhysical ExertionAMP-Activated Protein KinasesAnimalsBiomarkersBlood GlucoseCaseinsEnergy MetabolismGlucoseGlycogenInsulinMaleMice, Inbred C57BLMuscle, SkeletalPhosphorylationAMP-Activated Protein KinasesBiomarkersBlood GlucoseCaseinsGlucoseGlycogenInsulincasein peptideenergy expenditureinsulin signalingmuscle glycogenpost-exercise

Identifiers

PMID29891805
PMCPMC6024860
OpenAlexW2808541246

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.