Evidence map›Paper›PMID 29891789›Full record

ArticleInternational journal of molecular sciences2018

Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.

Mohamed F Zayed, Sahar Ahmed, Saleh Ihmaid, Hany E A Ahmed, Heba S Rateb, Sabrin R M Ibrahim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  3. Design, Synthesis, and Biological Evaluation ofPharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mohamed F ZayedPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. mfzayed25@yahoo.com.
Sahar AhmedPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. smahmed@taibahu.edu.sa.
Saleh IhmaidPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. sihmaid@taibahu.edu.sa.
Hany E A AhmedPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. heahmad@taibahu.edu.sa.
Heba S RatebPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. hsahmed@taibahu.edu.sa.
Sabrin R M IbrahimPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 41477, Saudi Arabia. sribrahim@taibahu.edu.sa.
Taibah University · SAAl-Azhar University · EGMisr University for Science and Technology · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of new fluoroquinazolinone

Indexed as

Molecular Docking SimulationPolymerizationAntineoplastic AgentsBinding SitesCell DeathCell Line, TumorColchicineErbB ReceptorsErlotinib HydrochlorideHumansInhibitory Concentration 50QuinazolinonesTubulinAntineoplastic AgentsColchicineErbB ReceptorsErlotinib HydrochlorideQuinazolinonesTubulincytotoxicitydesignEGFR kinasefluoroquinazolinonetubulin inhibitors

Identifiers

PMID29891789
PMCPMC6032053
OpenAlexW2806813602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.