ArticleInternational journal of environmental research and public health2018
Dengue Infection Spectrum in Guangzhou: A Cross-Sectional Seroepidemiology Study among Community Residents between 2013 and 2015.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Socioeconomic risk markers of arthropod-borne virus (arbovirus) infections: a systematic literature review and meta-analysis.BMJ global health · 2022Pooled it
- Social Mixing Patterns and Chikungunya Reemergence Risk in French Polynesia.JAMA network open · 2026Article
- A Systematic Review and Meta-Analysis of Maternal Dengue Infection and Adverse Pregnancy Outcomes.Cureus · 2025Review
- Seroprevalence of dengue in the general population of a Chinese southwestern border city: a community-based cross-sectional study.BMC infectious diseases · 2025Article
- Flying under the radar - impact and factors influencing asymptomatic DENV infections.Frontiers in cellular and infection microbiology · 2023Review
- Dengue and Dengue Virus in Guangdong, China, 1978-2017: Epidemiology, Seroprevalence, Evolution, and Policies.Frontiers in medicine · 2022Article
- Potential Misdiagnosis between COVID-19 and Dengue Infection Using Rapid Serological Test.Infectious disease reports · 2021Article
- The Seroprevalence of Dengue Virus Infection and Its Association With Iron (Fe) Level in Pregnant Women in Guangzhou, China.Frontiers in medicine · 2021Article
- Current vector research challenges in the greater Mekong subregion for dengue, Malaria, and Other Vector-Borne Diseases: A report from a multisectoral workshop March 2019.PLoS neglected tropical diseases · 2020Article
- Risk Factors Associated with Dengue Virus Infection in Guangdong Province: A Community-Based Case-Control Study.International journal of environmental research and public health · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The majority of dengue virus infections are asymptomatic, which could potentially facilitate the transmission of dengue fever and increase the percentage of sever dengue fever manifestations. This cross-sectional study explored the sero-prevalence of dengue virus infection in Guangzhou to clarify the infection spectrum. In total, 2085 serum samples were collected from residents of 34 communities. All samples were selected from a 200,000-sample database holding serum collected from community residents living in Liwan and Yuexiu districts of Guangzhou between September 2013 and August 2015, and 17 to 28 individuals of each age group were chosen per month. Dengue immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies were tested by enzyme-linked immunosorbent assay. Symptomatic infected individuals were identified via follow-up questionnaires. Among 2085 serum samples, anti-dengue IgG and IgM positive rates were 11.80% and 3.98%, respectively. The IgG antibody positive rate increased with age and was higher in poorly educated people than in highly educated people and in married individuals than in single individuals. Approximately 96.71% of dengue virus infections and an estimated 13.68% of the whole population were asymptomatic. Such high asymptomatic-infection rates have an impact on the local spread of dengue fever. Stricter surveillance, such as a network of rapid diagnostic laboratories, screening of residents in the epidemic season, and other integrated control measures are necessary.
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