ReviewJournal of clinical medicine2018
The Role of Procalcitonin in the Diagnosis of Meningitis: A Literature Review.
Review in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 48 citations in OpenAlex.
- Mastoiditis With Pneumocephalus on CT: An Uncommon Clue to Underlying Bacterial Meningitis.Cureus · 2026Article
- Cerebrospinal fluid procalcitonin and neutrophil percentage: a combined biomarker for differentiating bacterial from tuberculous meningitis in antibiotic-pretreated patients.Frontiers in cellular and infection microbiology · 2026Article
- Article
- Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study.Journal of translational medicine · 2023Article
- Serum β-Defensin 2, A Novel Biomarker for the Diagnosis of Acute Infections.Diagnostics (Basel, Switzerland) · 2023Article
- The Diagnostic Value of Cerebrospinal Fluid Lactate for Detection of Sepsis in Community-Acquired Bacterial Meningitis.Diagnostics (Basel, Switzerland) · 2023Article
- Treatment of Ventriculitis and Meningitis After Neurosurgery Caused by Carbapenem-ResistantInfection and drug resistance · 2023Review
- Article
- Procalcitonin measurement in West Nile virus neuroinvasive disease: A first case series.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2021Article
- [Diagnostic value of serum amyloid A, procalcitonin and hypersensitive C-reactive protein for pulmonary tuberculosis complicated by pneumonia].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Prolonged Postoperative Pyrexia and Transient Nonnephrogenic Vasopressin-Analogue-Resistant Polyuria following Endoscopic Transsphenoidal Resection of an Infundibular Epidermoid Cyst.Case reports in neurological medicine · 2021Article
- Diagnostic value of combination of cranial MRI, serum homocysteine and procalcitonin for hyperbilirubinemia complicated with brain injury in neonates.Experimental and therapeutic medicine · 2020Article
- Diagnostic Value of Serum Procalcitonin in Patients with Convulsion in Emergency Department, an Observational Study.Antibiotics (Basel, Switzerland) · 2020Article
- Clinical, Pathological and Microbiological Evaluation of Diabetic Foot Syndrome.Medicina (Kaunas, Lithuania) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review the current published literature on the use of procalcitonin as a diagnostic and prognostic marker in adult patients with meningitis.
methodsWe conducted a PubMed search to identify all relevant publications regarding the diagnostic and prognostic value of serum procalcitonin in patients with a known or suspected central nervous system infection. We also reviewed the bibliographies of all identified manuscripts in an attempt to identify additional relevant references.
resultsA significant body of evidence suggests that serum procalcitonin has a promising role and can be a useful biomarker in the assessment of patients with meningitis.
conclusionsOur literature review suggests that data on the role of Cerebrospinal Fluid (CSF) procalcitonin are limited, whereas serum procalcitonin (S⁻PCT) is probably a useful tool in the evaluation of patients with a known or suspected central nervous system infection and can help distinguish between bacterial and viral meningitis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.