Evidence map›Paper›PMID 29891777›Full record

ArticleInternational journal of molecular sciences2018

Caveolin-1 Scaffolding Domain Peptides Alleviate Liver Fibrosis by Inhibiting TGF-β1/Smad Signaling in Mice.

Jing Lu, Jie Zhang, Yan Wang, Quan Sun

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Revolutionizing Autoimmune Research: The Role of Caveolin-1.Immunity, inflammation and disease · 2025
    Review
  2. Ciliary and Non-Ciliary Roles of IFT88 in Development and Diseases.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing LuDepartment of Laboratory Animal Science, School of Basic Medical Science, Capital Medical University, Beijing 100069, China. lujing@ccmu.edu.cn.
Jie ZhangDepartment of Laboratory Animal Science, School of Basic Medical Science, Capital Medical University, Beijing 100069, China. 13811560655@163.com.
Yan WangDepartment of Laboratory Animal Science, School of Basic Medical Science, Capital Medical University, Beijing 100069, China. Sugar06240713@163.com.
Quan SunDepartment of Laboratory Animal Science, School of Basic Medical Science, Capital Medical University, Beijing 100069, China. sunquan@ccmu.edu.cn.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis is the common pathological process characterized by activation of hepatic stellate cells (HSCs) and overproduction of extracellular matrix (ECM). Caveolin-1 (Cav1), the principal component of caveolae, is regarded as an important inhibitor of multiple signaling molecules including transforming growth factor β1(TGF-β1) signaling. To evaluate the role of Cav1 in liver fibrosis, Cav1 deficient (Cav1

Indexed as

Signal TransductionAnimalsCarbon TetrachlorideCaveolin 1Cells, CulturedCollagen Type IDown-RegulationHepatic Stellate CellsInflammationLiver CirrhosisMaleMiceMice, KnockoutPeptidesPhosphorylationProtein DomainsCarbon TetrachlorideCaveolin 1Collagen Type IPeptidesSmad ProteinsTransforming Growth Factor beta1caveolin-1hepatic stellate cellsliver fibrosisTGF-β1/Smad signaling

Identifiers

PMID29891777
PMCPMC6032240
OpenAlexW2808164572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.