ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer.
Abstract read
In one paragraph
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Multifocal cohort analysis unveils cell types associated with regional lymph node seeding in prostate cancer.Genome medicine · 2026Article
- Evolutionary dynamics of early and late mutational signatures in metastatic cancer.Frontiers in bioinformatics · 2026Article
- Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5.In vitro cellular & developmental biology. Animal · 2025Article
- Genome-level selection in tumors as a universal marker of resistance to therapy.Nature communications · 2025Article
- Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1.Journal of ovarian research · 2024Article
- Modeling the Effect of Spatial Structure on Solid Tumor Evolution and Circulating Tumor DNA Composition.Cancers · 2024Article
- The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer.Annals of medicine · 2023Article
- Modeling the effect of spatial structure on solid tumor evolution and ctDNA composition.bioRxiv : the preprint server for biology · 2023Article
- Tumor Characteristics Associated with Axillary Nodal Positivity in Triple Negative Breast Cancer.Diseases (Basel, Switzerland) · 2023Article
- A phylogenetic approach to study the evolution of somatic mutational processes in cancer.Communications biology · 2022Article
- Article
- Simvastatin induced ferroptosis for triple-negative breast cancer therapy.Journal of nanobiotechnology · 2021Article
- Tracking Cancer Evolution through the Disease Course.Cancer discovery · 2021Review
- Proteomics of REPLICANT perfusate detects changes in the metastatic lymph node microenvironment.NPJ breast cancer · 2021Article
- Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer.Genomics, proteomics & bioinformatics · 2021Article
- The role of single-cell sequencing in studying tumour evolution.Faculty reviews · 2021Review
- Systems Biology and Experimental Model Systems of Cancer.Journal of personalized medicine · 2020Review
- Prognostic factors in metastatic breast cancer: a prospective single-centre cohort study in a Finnish University Hospital.BMJ open · 2020Article
- EBV-LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer.Cancer medicine · 2020Article
- Effect of neoadjuvant therapy on breast cancer biomarker profile.BMC cancer · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Peter Barry *Department of Surgery, Breast Unit, Royal Marsden Hospital, London, United Kingdom.
Alexandra Vatsiou *Evolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Inmaculada Spiteri *Evolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Daniel NicholEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
George D CresswellEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Ahmet AcarEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Nicholas TrahearnEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Sarah HrebienBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Isaac Garcia-MurillasBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Kate ChkhaidzeEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Luca ErminiCentre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Ian Said HuntingfordDepartment of Pathology, Mater Dei Hospital, Msida, Malta.
Hannah CottomBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Lila ZabagloRalph Lauren Breast Cancer Research Centre, Royal Marsden Hospital, London, United Kingdom.
Konrad KoelbleRalph Lauren Breast Cancer Research Centre, Royal Marsden Hospital, London, United Kingdom.
Saira KhaliqueRalph Lauren Breast Cancer Research Centre, Royal Marsden Hospital, London, United Kingdom.
Jennifer E RusbyDepartment of Surgery, Breast Unit, Royal Marsden Hospital, London, United Kingdom.
Francesca MuscaraDepartment of Surgery, Breast Unit, Royal Marsden Hospital, London, United Kingdom.
Mitch DowsettRalph Lauren Breast Cancer Research Centre, Royal Marsden Hospital, London, United Kingdom.
Carlo C MaleyEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Rachael NatrajanBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Yinyin YuanCentre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
Gaia SchiavonBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Nicholas TurnerBreast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Andrea SottorivaEvolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom. andrea.sottoriva@icr.ac.uk.
Funding
PHYLOGENIES of Barrett's Esophagus LineagesP01CA091955 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY · 2002 to 2019
$35.9MMolecular, Cellular and Tissue Characterization UnitU2CCA233254 · NCI · DUKE UNIVERSITY · PI HWANG, E.SHELLEY · 2018 to 2023
$11.4MThe Role of the Microbiome in Cancer Suppression and Susceptibility Across SpeciesU54CA217376 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MALEY, CARLO, SHIBATA, DARRYL K · 2018 to 2022
$8.6MModeling Neoplastic Progression in Barrett's Esophagus - Renewal -2R01CA140657 · NCI · WISTAR INSTITUTE · PI Carlo Maley · 2009 to 2026
$5.0MApplication of Evolutionary Principles to Maintain Cancer Control (PQ21)R01CA170595 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GATENBY, ROBERT A · 2012 to 2015
$2.1M(PQC3) Genomic Diversity and Microenvironment as Drivers of Metastasis in DCISR01CA185138 · NCI · DUKE UNIVERSITY · PI HWANG, E.SHELLEY, MALEY, CARLO · 2014 to 2017
$2.0MCancer Research UK 22909Cancer Research UK A22909NCI NIH HHS P01 CA091955NCI NIH HHS R01 CA140657NCI NIH HHS R01 CA170595NCI NIH HHS R01 CA185138NCI NIH HHS U2C CA233254NCI NIH HHS U54 CA217376Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAgedAged, 80 and overAxillaBreast NeoplasmsCirculating Tumor DNAClonal EvolutionFemaleGene Expression Regulation, NeoplasticHumansLymphatic MetastasisLymph NodesMiddle AgedNeoplasm ProteinsNeoplasm StagingCirculating Tumor DNANeoplasm Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.