Evidence map›Paper›PMID 29891718›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Genetics of alternative splicing evolution during sunflower domestication.

Chris C R Smith, Silas Tittes, J Paul Mendieta, Erin Collier-Zans, Heather C Rowe, Loren H Rieseberg, Nolan C Kane

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Ancestral splice variation is a key substrate for rapid diversification in African cichlids.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  15. Integrative analysis in Pinus revealed long-term heat stress splicing memory.The Plant journal : for cell and molecular biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chris C R SmithDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309-0334; chriscs@colorado.edu.ORCID 0000-0002-6470-3413
Silas TittesDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309-0334.
J Paul MendietaDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309-0334.
Erin Collier-ZansDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309-0334.
Heather C RoweDepartment of Botany, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Loren H RiesebergDepartment of Botany, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Nolan C KaneDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309-0334.ORCID 0000-0001-9133-6543
University of Colorado Boulder · USUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alternative splicing enables organisms to produce the diversity of proteins necessary for multicellular life by using relatively few protein-coding genes. Although differences in splicing have been identified among divergent taxa, the shorter-term evolution of splicing is understudied. The origins of novel splice forms, and the contributions of alternative splicing to major evolutionary transitions, are largely unknown. This study used transcriptomes of wild and domesticated sunflowers to examine splice differentiation and regulation during domestication. We identified substantial splicing divergence between wild and domesticated sunflowers, mainly in the form of intron retention. Transcripts with divergent splicing were enriched for seed-development functions, suggesting that artificial selection impacted splicing patterns. Mapping of quantitative trait loci (QTLs) associated with 144 differential splicing cases revealed primarily

Indexed as

Alternative SplicingEvolution, MolecularDomesticationHelianthusPlant BreedingPlant ProteinsProtein IsoformsQuantitative Trait LociRNA, PlantSpliceosomesTranscriptomePlant ProteinsProtein IsoformsRNA, Plantalternative splicingdomesticationquantitative trait lociRNA-seq

Identifiers

PMID29891718
PMCPMC6042098
OpenAlexW2808039435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.