Evidence map›Paper›PMID 29891607›Full record

ArticleAntimicrobial agents and chemotherapy2018

Prevalence of a Cefazolin Inoculum Effect Associated with

Sheila K Wang, Annette Gilchrist, Anastasia Loukitcheva, Balbina J Plotkin, Ira M Sigar, Alan E Gross, J Nicholas O'Donnell, Natasha Pettit, Amy Buros, Tristan O'Driscoll and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Observational
  2. Development of a rapid diagnostic test for the cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus: Cefinase disk direct (CDD) test.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Effectiveness and safety of cefazolin versus cloxacillin in endocarditis due to methicillin-susceptible Staphylococcus spp.: a multicenter propensity weighted cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Epidemiology and impact of methicillin-sensitiveAntimicrobial agents and chemotherapy · 2023
    Article
  11. Antimicrobial Treatment ofAntibiotics (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Inoculum effect of β-lactam antibiotics.The Journal of antimicrobial chemotherapy · 2019
    Review
  20. Dissemination Of t437-SCCInfection and drug resistance · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sheila K WangDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA swangx@midwestern.edu.
Annette GilchristDepartment of Pharmaceutical Sciences, Midwestern University, Downers Grove, Illinois, USA.
Anastasia LoukitchevaDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA.
Balbina J PlotkinDepartment of Microbiology and Immunology, Midwestern University, Downers Grove, Illinois, USA.
Ira M SigarDepartment of Microbiology and Immunology, Midwestern University, Downers Grove, Illinois, USA.
Alan E GrossDepartment of Pharmacy Practice, University of Illinois at Chicago, Chicago, Illinois, USA.
J Nicholas O'DonnellDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA.
Natasha PettitDepartment of Pharmacy, University of Chicago Medical Center, Chicago, Illinois, USA.
Amy BurosMidwestern University, Glendale, Arizona, USA.
Tristan O'DriscollDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA.
Nathaniel J RhodesDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA.ORCID 0000-0002-0018-5434
Cindy BethelDepartment of Pathology, University of Chicago Medical Center, Chicago, Illinois, USA.
John SegretiDivision of Infectious Diseases, Rush University Medical Center, Chicago, Illinois, USA.
Angella Charnot-KatsikasDepartment of Pathology, University of Chicago Medical Center, Chicago, Illinois, USA.
Kamaljit SinghDivision of Infectious Diseases, Rush University Medical Center, Chicago, Illinois, USA.
Marc H ScheetzDepartment of Pharmacy Practice, Midwestern University, Downers Grove, Illinois, USA.ORCID 0000-0002-1091-6130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of cefazolin with high-inoculum methicillin-susceptible

Indexed as

Genes, BacterialAcademic Medical CentersAnti-Bacterial AgentsBacterial LoadCefazolinChicagoHumansMicrobial Sensitivity TestsPrevalenceStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCefazolinbeta-lactamasesblaZcefazolininoculum effectMSSAStaphylococcus aureus

Identifiers

PMID29891607
PMCPMC6105856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.