Evidence map›Paper›PMID 29891601›Full record

ArticleAntimicrobial agents and chemotherapy2018

Potency of Solithromycin against Fast- and Slow-Growing Chlamydial Organisms.

Leiqiong Gao, Yao Wang, Ziyu Hua, Enmei Liu, Li Shen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Leiqiong Gao *Department of Pulmonary Medicine, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Yao Wang *Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Ziyu HuaDepartment of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Enmei LiuDepartment of Pulmonary Medicine, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Li ShenDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA lshen@lsuhsc.edu.
Children's Hospital of Chongqing Medical University · CNLouisiana State University Health Sciences Center New Orleans · US

Funding

A molecular switch of the type III secretion system in Chlamydia trachomatisR56AI093565 · NIAID · LSU HEALTH SCIENCES CENTER · PI SHEN, LI · 2012 to 2012
$355k
NIAID NIH HHS R56 AI093565
6 · The paper itself

Abstract

Evidence is provided that solithromycin is a bactericidal against not only fast-growing chlamydial organisms but also those slowed by gamma interferon (IFN-γ)

Indexed as

Anti-Bacterial AgentsBacterial ProteinsChlamydia trachomatisInterferon-gammaMacrolidesTriazolesAnti-Bacterial AgentsBacterial ProteinsInterferon-gammaMacrolidessolithromycinTriazolesantibacterial mechanismbacterial translationChlamydia trachomatisgamma interferongreen fluorescent proteinobligate intracellular bacteriumpersistent infectionproductive infectionsolithromycintype III secretion system

Identifiers

PMID29891601
PMCPMC6105862
OpenAlexW2805844486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.