Evidence map›Paper›PMID 29891599›Full record

ArticleAntimicrobial agents and chemotherapy2018

Karen Joy Shaw, Wiley A Schell, Jonathan Covel, Gisele Duboc, C Giamberardino, Mili Kapoor, Molly Moloney, Quinlyn A Soltow, Jennifer L Tenor, Dena L Toffaletti and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 115 citations in OpenAlex.

  1. Trial
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  5. New Perspectives on Antimicrobial Agents: Fosmanogepix.Antimicrobial agents and chemotherapy · 2026
    Review
  6. Manogepix demonstrates potentAntimicrobial agents and chemotherapy · 2026
    Article
  7. Article
  8. Review
  9. Review
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  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Karen Joy ShawAmplyx Pharmaceuticals, San Diego, California, USA kshaw@amplyx.com.
Wiley A SchellDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Jonathan CovelAmplyx Pharmaceuticals, San Diego, California, USA.
Gisele DubocDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
C GiamberardinoDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Mili KapoorAmplyx Pharmaceuticals, San Diego, California, USA.
Molly MoloneyAmplyx Pharmaceuticals, San Diego, California, USA.
Quinlyn A SoltowAmplyx Pharmaceuticals, San Diego, California, USA.
Jennifer L TenorDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Dena L ToffalettiDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Michael TrzossAmplyx Pharmaceuticals, San Diego, California, USA.
Peter WebbAmplyx Pharmaceuticals, San Diego, California, USA.
John R PerfectDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Amplyx Pharmaceuticals (United States) · USDuke Medical Center · US

Funding

Trehalose Pathway for Antifungal Targets and InhibitorsP01AI104533 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2015 to 2019
$9.0M
Pathobiology of C. neoformans in the Central Nervous SystemR01AI073896 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2008 to 2018
$4.4M
NIAID NIH HHS P01 AI104533NIAID NIH HHS R01 AI073896
6 · The paper itself

Abstract

Cryptococcal meningitis (CM), caused primarily by

Indexed as

Administration, OralAmidohydrolasesAminopyridinesAnimalsAntifungal AgentsBrainCryptococcus gattiiCryptococcus neoformansDisease Models, AnimalDose-Response Relationship, DrugDrug CombinationsDrug SynergismFluconazoleFungal ProteinsHumansInjections, IntraperitonealamidaseAmidohydrolasesAminopyridinesAntifungal AgentsAPX001ADrug CombinationsFluconazoleFungal ProteinsIsoxazolesOrganophosphatesProdrugs1-aminobenzotriazoleantifungalAPX001APX001ACryptococcusGwt1infection model

Identifiers

PMID29891599
PMCPMC6105804
OpenAlexW2805470919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.