Evidence map›Paper›PMID 29891552›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Opposing Effects of IL-1Ra and IL-36Ra on Innate Immune Response to

Nan Gao, Rao Me, Chenyang Dai, Berhane Seyoum, Fu-Shin X Yu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Nanozymes for Treating Ocular Diseases.Advanced healthcare materials · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Non-immune and immune functions of interleukin-36γ suppress epithelial repair at the ocular surface.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  11. Review
  12. IL-36α Enhances Host Defense againstJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. IL-17 PromotesJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Nan GaoDepartment of Ophthalmology, Wayne State University School of Medicine, Detroit, MI 48201.
Rao MeDepartment of Ophthalmology, Wayne State University School of Medicine, Detroit, MI 48201.
Chenyang DaiDepartment of Ophthalmology, Wayne State University School of Medicine, Detroit, MI 48201.
Berhane SeyoumDivision of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201.ORCID 0000-0003-0087-5096
Fu-Shin X YuDepartment of Ophthalmology, Wayne State University School of Medicine, Detroit, MI 48201; fyu@med.wayne.edu.ORCID 0000-0002-8517-2738
Wayne State University · US

Funding

VISION RESEARCH--COREP30EY004068 · NEI · WAYNE STATE UNIVERSITY · PI LINDA D HAZLETT · 1985 to 2026
$13.2M
MOLECULAR REGULATION OF CORNEAL WOUND HEALINGR01EY010869 · NEI · WAYNE STATE UNIVERSITY · PI YU, FU-SHIN X · 1995 to 2023
$7.7M
Mechanisms of flagellin-induced protection against microbial keratitisR01EY017960 · NEI · WAYNE STATE UNIVERSITY · PI YU, FU-SHIN X · 2008 to 2020
$4.8M
NEI NIH HHS P30 EY004068NEI NIH HHS R01 EY010869NEI NIH HHS R01 EY017960
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCalgranulin BCell MovementCells, CulturedChemokine CXCL10CorneaHumansImmunity, InnateKeratinocytesKeratitisMiceMice, Inbred C57BLPseudomonas aeruginosaPseudomonas InfectionsReceptors, CXCR3Receptors, Interleukin-1Calgranulin BChemokine CXCL10Cxcr3 protein, mouseIl1rl2 protein, mouseReceptors, CXCR3Receptors, Interleukin-1

Identifiers

PMID29891552
PMCPMC6039246
OpenAlexW2808188830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.